LigaSure Use Decreases Intraoperative Blood Loss Volume and Blood Transfusion Volume in Sarcoma Surgery

Nicole L. Levine, Yidan Zhang, Bang H. Hoang, Rui Yang, Zachary H. Jurkowski, Michael E. Roth, Jonathan B. Gill, Yungtai Lo, Ruth E. Eisenberg, Mikhail Bekarev, Richard G. Gorlick, David S. Geller

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Introduction:The LigaSure system has been successfully used in thoracic and abdominal surgery. However, to date, its use in the resection of sarcomas has not been systematically studied. We aimed to determine whether the use of the LigaSure system reduces blood loss and blood transfusion volumes in sarcoma surgery.Methods:One hundred forty-two consecutive patients who underwent sarcoma surgeries between July 2010 and October 2016 were included. Conventional electrocautery alone (n = 91) and with LigaSure (n = 51) were compared. Case-matched samples (n = 46) from each group were additionally compared.Results:The use of the LigaSure system resulted in a significant decrease in mean intraoperative blood loss (P = 0.02) and blood transfusion volume (P = 0.04). Likewise, a significant decrease in both mean and median intraoperative blood loss (P = 0.003; P < 0.0001) was seen with LigaSure in the case-matched analysis. In the soft-tissue sarcoma subgroup, a significant decrease was observed in mean hemoglobin reduction (P = 0.03) and mean intraoperative blood loss with LigaSure (P = 0.04). No adverse perioperative complications attributed to the LigaSure system were identified.Conclusions:The LigaSure vessel sealing and dividing system is a safe and effective hemostatic tool for deep dissection in bone and soft-tissue sarcoma surgery.

Original languageEnglish (US)
Pages (from-to)841-847
Number of pages7
JournalJournal of the American Academy of Orthopaedic Surgeons
Issue number22
StatePublished - Nov 15 2019

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine


Dive into the research topics of 'LigaSure Use Decreases Intraoperative Blood Loss Volume and Blood Transfusion Volume in Sarcoma Surgery'. Together they form a unique fingerprint.

Cite this