Length-normalized pulse photoplethysmography: A noninvasive method to measure blood hemoglobin

Thomas K. Aldrich; Mark Moosikasuwan; Samir D. Shah; Kedar S. Deshpande

doi:10.1114/1.1527046

Length-normalized pulse photoplethysmography: A noninvasive method to measure blood hemoglobin

Thomas K. Aldrich
, Mark Moosikasuwan
, Samir D. Shah
, Kedar S. Deshpande

Medicine

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Abstract

A study was performed to demonstrate that length-normalized pulse photoplethysmography, with measurement of changing attenuation to changing length ratios (D₉₀₅/l) proximal to the fingernail during arterial pulsations, may be feasible as a noninvasive technique to measure blood hemoglobin. Some 24 subjects were tested, including several with very severe anemia. In these subjects, with normal S_pO₂, normal metHb and normal to near-normal COHb, using crude instrumentation adapted from off-the-shelf equipment, close correlation was found between [Hb] and D₉₀₅/l, high sensitivity for the detection of anemia, and an adequate specificity for a screening tool.

Original language	English (US)
Pages (from-to)	1291-1298
Number of pages	8
Journal	Annals of Biomedical Engineering
Volume	30
Issue number	10
DOIs	https://doi.org/10.1114/1.1527046
State	Published - 2002

Keywords

Absorption
Anemia
Clinical monitoring
Optical properties
Pulse oximetry
Sonomicrometry

ASJC Scopus subject areas

Biomedical Engineering

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10.1114/1.1527046

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title = "Length-normalized pulse photoplethysmography: A noninvasive method to measure blood hemoglobin",

abstract = "A study was performed to demonstrate that length-normalized pulse photoplethysmography, with measurement of changing attenuation to changing length ratios (D905/l) proximal to the fingernail during arterial pulsations, may be feasible as a noninvasive technique to measure blood hemoglobin. Some 24 subjects were tested, including several with very severe anemia. In these subjects, with normal SpO2, normal metHb and normal to near-normal COHb, using crude instrumentation adapted from off-the-shelf equipment, close correlation was found between [Hb] and D905/l, high sensitivity for the detection of anemia, and an adequate specificity for a screening tool.",

keywords = "Absorption, Anemia, Clinical monitoring, Optical properties, Pulse oximetry, Sonomicrometry",

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language = "English (US)",

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pages = "1291--1298",

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T1 - Length-normalized pulse photoplethysmography

T2 - A noninvasive method to measure blood hemoglobin

AU - Aldrich, Thomas K.

AU - Moosikasuwan, Mark

AU - Shah, Samir D.

AU - Deshpande, Kedar S.

PY - 2002

Y1 - 2002

N2 - A study was performed to demonstrate that length-normalized pulse photoplethysmography, with measurement of changing attenuation to changing length ratios (D905/l) proximal to the fingernail during arterial pulsations, may be feasible as a noninvasive technique to measure blood hemoglobin. Some 24 subjects were tested, including several with very severe anemia. In these subjects, with normal SpO2, normal metHb and normal to near-normal COHb, using crude instrumentation adapted from off-the-shelf equipment, close correlation was found between [Hb] and D905/l, high sensitivity for the detection of anemia, and an adequate specificity for a screening tool.

AB - A study was performed to demonstrate that length-normalized pulse photoplethysmography, with measurement of changing attenuation to changing length ratios (D905/l) proximal to the fingernail during arterial pulsations, may be feasible as a noninvasive technique to measure blood hemoglobin. Some 24 subjects were tested, including several with very severe anemia. In these subjects, with normal SpO2, normal metHb and normal to near-normal COHb, using crude instrumentation adapted from off-the-shelf equipment, close correlation was found between [Hb] and D905/l, high sensitivity for the detection of anemia, and an adequate specificity for a screening tool.

KW - Absorption

KW - Anemia

KW - Clinical monitoring

KW - Optical properties

KW - Pulse oximetry

KW - Sonomicrometry

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JO - Annals of Biomedical Engineering

JF - Annals of Biomedical Engineering

IS - 10

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Length-normalized pulse photoplethysmography: A noninvasive method to measure blood hemoglobin

Abstract

Keywords

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