L-Dihydroxyphenylalanine induces melanin production by members of the genus Trichosporon

Maria Helena Galdino Figueiredo-Carvalho, Fábio B. dos Santos, Joshua D. Nosanchuk, Rosely M. Zancope-Oliveira, Rodrigo Almeida-Paes

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13 Scopus citations


Melanization of members of the genus Trichosporon is poorly described. In this study, six strains, including two clinical isolates, from four different species (Trichosporon asahii, T. asteroides, T. inkin, and T. mucoides) were grown in culture media with or without L-dihydroxyphenylalanine (L-DOPA). Each strain produced a brownish pigment compatible with melanin when cultured in presence of L-DOPA, suggesting that these species are able to produce eumelanin. L-tyrosine was not able to elicit any type of pigment production on cultures. As eumelanin is produced by several fungi during parasitism, this pigment may contribute to Trichosporon virulence.

Original languageEnglish (US)
Pages (from-to)988-991
Number of pages4
JournalFEMS Yeast Research
Issue number6
StatePublished - 2014


  • L-DOPA
  • Melanin
  • Trichosporon

ASJC Scopus subject areas

  • Microbiology
  • Applied Microbiology and Biotechnology


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