It's not over till the last glomerulus forms

Rosemary Thomas, Frederick J. Kaskel

Research output: Contribution to journalComment/debatepeer-review

5 Scopus citations


The Brenner hypothesis postulated that low birth weight and decreased nephron number at birth are linked to chronic kidney disease and systemic hypertension in adulthood. To date, little is known about the effect of extrauterine growth retardation (EUGR) on adult kidney disease. Bacchetta et al. present novel data using inulin to show a decrease in renal function for premature children with EUGR. The role of protein nutrition and timing in nephrogenesis is discussed.

Original languageEnglish (US)
Pages (from-to)361-363
Number of pages3
JournalKidney international
Issue number4
StatePublished - Aug 2009

ASJC Scopus subject areas

  • Nephrology


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