Intramuscular triamcinolone in severe asthma

Sergio Salmeron; Olivier Sitbon; Philippe Herve; Gérald Simonneau; Pierre Duroux; René Caquet; S. Scott Nicholas; Joseph C. Kidney; R. W. Fuller; Peter J. Barnes; S. Capewell; D. T. McLeod; Raja G. Ogirala; Thomas K. Aldrich; David J. Prezant; M. Henry Williams

doi:10.1056/NEJM199108083250613

Intramuscular triamcinolone in severe asthma

Sergio Salmeron, Olivier Sitbon, Philippe Herve, Gérald Simonneau, Pierre Duroux, René Caquet, S. Scott Nicholas, Joseph C. Kidney, R. W. Fuller, Peter J. Barnes, S. Capewell, D. T. McLeod, Raja G. Ogirala, Thomas K. Aldrich, David J. Prezant, M. Henry Williams

Medicine

Research output: Contribution to journal › Letter › peer-review

Abstract

The article by Ogirala and colleagues (Feb. 28 issue)¹ concerning high-dose intramuscular triamcinolone in severe, chronic, life-threatening asthma prompts the following comments. First, in our view the patients were probably undertreated on entry into the study: the maintenance dose of prednisone was 10 mg daily or less in half the patients (Patients 2, 6, 7, 9, 10, and 12), which is a low dose for patients at risk for fatal asthma.² Moreover, the maintenance dose of inhaled corticosteroids (triamcinolone acetonide) is not mentioned. Second, the dose of prednisone used in the study (15 mg daily) is not …

Original language	English (US)
Pages (from-to)	429-431
Number of pages	3
Journal	New England Journal of Medicine
Volume	325
Issue number	6
DOIs	https://doi.org/10.1056/NEJM199108083250613
State	Published - Aug 8 1991

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Medicine(all)

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10.1056/NEJM199108083250613

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Salmeron, S., Sitbon, O., Herve, P., Simonneau, G., Duroux, P., Caquet, R., Nicholas, S. S., Kidney, J. C., Fuller, R. W., Barnes, P. J., Capewell, S., McLeod, D. T., Ogirala, R. G., Aldrich, T. K., Prezant, D. J., & Williams, M. H. (1991). Intramuscular triamcinolone in severe asthma. New England Journal of Medicine, 325(6), 429-431. https://doi.org/10.1056/NEJM199108083250613

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title = "Intramuscular triamcinolone in severe asthma",

abstract = "The article by Ogirala and colleagues (Feb. 28 issue)1 concerning high-dose intramuscular triamcinolone in severe, chronic, life-threatening asthma prompts the following comments. First, in our view the patients were probably undertreated on entry into the study: the maintenance dose of prednisone was 10 mg daily or less in half the patients (Patients 2, 6, 7, 9, 10, and 12), which is a low dose for patients at risk for fatal asthma.2 Moreover, the maintenance dose of inhaled corticosteroids (triamcinolone acetonide) is not mentioned. Second, the dose of prednisone used in the study (15 mg daily) is not …",

author = "Sergio Salmeron and Olivier Sitbon and Philippe Herve and G{\'e}rald Simonneau and Pierre Duroux and Ren{\'e} Caquet and Nicholas, {S. Scott} and Kidney, {Joseph C.} and Fuller, {R. W.} and Barnes, {Peter J.} and S. Capewell and McLeod, {D. T.} and Ogirala, {Raja G.} and Aldrich, {Thomas K.} and Prezant, {David J.} and Williams, {M. Henry}",

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doi = "10.1056/NEJM199108083250613",

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AU - Salmeron, Sergio

AU - Sitbon, Olivier

AU - Herve, Philippe

AU - Simonneau, Gérald

AU - Duroux, Pierre

AU - Caquet, René

AU - Nicholas, S. Scott

AU - Kidney, Joseph C.

AU - Fuller, R. W.

AU - Barnes, Peter J.

AU - Capewell, S.

AU - McLeod, D. T.

AU - Ogirala, Raja G.

AU - Aldrich, Thomas K.

AU - Prezant, David J.

AU - Williams, M. Henry

PY - 1991/8/8

Y1 - 1991/8/8

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AB - The article by Ogirala and colleagues (Feb. 28 issue)1 concerning high-dose intramuscular triamcinolone in severe, chronic, life-threatening asthma prompts the following comments. First, in our view the patients were probably undertreated on entry into the study: the maintenance dose of prednisone was 10 mg daily or less in half the patients (Patients 2, 6, 7, 9, 10, and 12), which is a low dose for patients at risk for fatal asthma.2 Moreover, the maintenance dose of inhaled corticosteroids (triamcinolone acetonide) is not mentioned. Second, the dose of prednisone used in the study (15 mg daily) is not …

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Intramuscular triamcinolone in severe asthma

Abstract

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