Intracranial Metastases

Mary R. Welch, Thomas J. Kaley

Research output: Chapter in Book/Report/Conference proceedingChapter


Brain metastases are among the most common and feared complications of cancer. Over the past decades, advances in our understanding of cancer biology along with refinements of existing treatment modalities have begun to challenge therapeutic nihilism. Surgical resection and radiation remain mainstays of treatment, but debate exists over their appropriate use and timing. In addition to outlining the epidemiology, presentation, and work-up of the patient with brain metastases, this chapter explores these controversies and outlines a rational approach to management.

Original languageEnglish (US)
Title of host publicationNeuro-oncology
Subtitle of host publicationFirst Edition
PublisherBlackwell Publishing Ltd
Number of pages14
ISBN (Print)9780470655757
StatePublished - Feb 29 2012
Externally publishedYes


  • Anticonvulsants
  • Brain metastases
  • Corticosteroids
  • Molecularly targeted agents
  • Stereotactic radiosurgery (SRS)
  • Whole-brain radiation (WBRT)

ASJC Scopus subject areas

  • General Neuroscience
  • General Medicine


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