Intracellular crystal formation as a mechanism of cytotoxicity in murine pulmonary Cryptococcus neoformans infection

M. Feldmesser; Y. Kress; A. Casadevall

doi:10.1128/IAI.69.4.2723-2727.2001

Intracellular crystal formation as a mechanism of cytotoxicity in murine pulmonary Cryptococcus neoformans infection

M. Feldmesser, Y. Kress, A. Casadevall

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

Rod-like crystalline structures formed during eosinophilic Cryptococcus neoformans pneumonia in C57BL/6 mice. Crystals were found associated with yeast cells and free in host cell cytoplasm. The crystals apparently formed because of the interaction of a host protein with the cryptococcal polysaccharide. Crystal formation likely contributes to pathogenesis by causing cellular damage.

Original language	English (US)
Pages (from-to)	2723-2727
Number of pages	5
Journal	Infection and immunity
Volume	69
Issue number	4
DOIs	https://doi.org/10.1128/IAI.69.4.2723-2727.2001
State	Published - 2001
Externally published	Yes

ASJC Scopus subject areas

Parasitology
Microbiology
Immunology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1128/IAI.69.4.2723-2727.2001

Cite this

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title = "Intracellular crystal formation as a mechanism of cytotoxicity in murine pulmonary Cryptococcus neoformans infection",

abstract = "Rod-like crystalline structures formed during eosinophilic Cryptococcus neoformans pneumonia in C57BL/6 mice. Crystals were found associated with yeast cells and free in host cell cytoplasm. The crystals apparently formed because of the interaction of a host protein with the cryptococcal polysaccharide. Crystal formation likely contributes to pathogenesis by causing cellular damage.",

author = "M. Feldmesser and Y. Kress and A. Casadevall",

year = "2001",

doi = "10.1128/IAI.69.4.2723-2727.2001",

language = "English (US)",

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journal = "Infection and immunity",

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publisher = "American Society for Microbiology",

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TY - JOUR

T1 - Intracellular crystal formation as a mechanism of cytotoxicity in murine pulmonary Cryptococcus neoformans infection

AU - Feldmesser, M.

AU - Kress, Y.

AU - Casadevall, A.

PY - 2001

Y1 - 2001

N2 - Rod-like crystalline structures formed during eosinophilic Cryptococcus neoformans pneumonia in C57BL/6 mice. Crystals were found associated with yeast cells and free in host cell cytoplasm. The crystals apparently formed because of the interaction of a host protein with the cryptococcal polysaccharide. Crystal formation likely contributes to pathogenesis by causing cellular damage.

AB - Rod-like crystalline structures formed during eosinophilic Cryptococcus neoformans pneumonia in C57BL/6 mice. Crystals were found associated with yeast cells and free in host cell cytoplasm. The crystals apparently formed because of the interaction of a host protein with the cryptococcal polysaccharide. Crystal formation likely contributes to pathogenesis by causing cellular damage.

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U2 - 10.1128/IAI.69.4.2723-2727.2001

DO - 10.1128/IAI.69.4.2723-2727.2001

M3 - Article

C2 - 11254641

AN - SCOPUS:0035083052

SN - 0019-9567

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JO - Infection and immunity

JF - Infection and immunity

IS - 4

ER -

Intracellular crystal formation as a mechanism of cytotoxicity in murine pulmonary Cryptococcus neoformans infection

Abstract

ASJC Scopus subject areas

UN SDGs

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