Interactions of cells from peritoneal dialysate with mesothelial cells and fibroblasts in culture.

A. Breborowicz, E. Balaskas, G. D. Oreopoulos, M. Vas, L. Martis, K. D. Serkes, D. G. Oreopoulos

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Peritoneal mesothelial cells and fibroblasts were co-cultured in vitro with peritoneal white blood cells (PWBC) obtained from CAPD patients, after an overnight exchange with 0.5% Dianeal or 2.5% Dianeal. Unstimulated PWBC inhibited proliferation of mesothelial cells and fibroblasts. Upon stimulation with lipoposaccharides (LPS), PWBC from the 0.5% dextrose exchange, enhanced the growth of mesothelial cells and fibroblasts, whereas when stimulated with LPS, PBWC from the 2.5% dextrose exchange increased only proliferation of fibroblasts.

Original languageEnglish (US)
Pages (from-to)7-10
Number of pages4
JournalAdvances in peritoneal dialysis. Conference on Peritoneal Dialysis
Volume8
StatePublished - 1992
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine

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