Raising the bar: The efficacy of bioorthogonal reactions for bioconjugation has been thoroughly evaluated in four different biological settings. Powered by the development of new biocompatible ligands, the copper-catalyzed azide-alkyne cycloaddition (see picture) has brought about unsurpassed bioconjugation efficiency, and thus it holds great promise as a highly potent and adaptive tool for a broader spectrum of biological applications.
|Original language||English (US)|
|Number of pages||6|
|Journal||Angewandte Chemie - International Edition|
|State||Published - Aug 22 2011|
- bioorthogonal reactions
- click chemistry
ASJC Scopus subject areas