Incidence and prevalence of antibody to hepatitis C virus in FDNY first responders before and after work at the World Trade Center disaster site

Mayris P. Webber; Yang Liu; Hillel W. Cohen; Theresa Schwartz; Michael D. Weiden; Kerry Kelly; Viola Ortiz; Rachel Zeig-Owens; Nadia Jaber; Hilary L. Colbeth; David J. Prezant

doi:10.1002/ajim.22871

Incidence and prevalence of antibody to hepatitis C virus in FDNY first responders before and after work at the World Trade Center disaster site

Mayris P. Webber, Yang Liu, Hillel W. Cohen, Theresa Schwartz, Michael D. Weiden, Kerry Kelly, Viola Ortiz, Rachel Zeig-Owens, Nadia Jaber, Hilary L. Colbeth, David J. Prezant

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Background: The goals of this study were to assess the impact of work at the World Trade Center (WTC) site in relation to new, post-9/11/2001 (9/11) antibody to hepatitis C Virus (anti-HCV); and, evaluate secular trends in WTC-exposed male Fire Department of New York City (FDNY) Firefighters and Emergency Medical Services (EMS) responders. Methods: FDNY monitors responder health through physical exams and routine blood work. We used descriptive statistics to compare trans-9/11 and post-9/11 incidence and to assess trends in prevalence from 2000 to 2012. Results: Trans-9/11 incidence of new anti-HCV was 0.42 per 100 persons compared with post-9/11 incidence of 0.34 (P = 0.68). Overall seroprevalence was 1.3%; rates declined from 1.79 per 100 to 0.49 per 100 over time (P < 0.0001). Conclusions: Work at the WTC was not associated with new infection. Biennial seroprevalence in responders declined over time, supporting the FDNY decision to discontinue routine annual testing in this cohort.

Original language	English (US)
Pages (from-to)	733-740
Number of pages	8
Journal	American Journal of Industrial Medicine
Volume	61
Issue number	9
DOIs	https://doi.org/10.1002/ajim.22871
State	Published - Sep 2018

Keywords

World Trade Center
firefighters
hepatitis C
incidence
prevalence

ASJC Scopus subject areas

Public Health, Environmental and Occupational Health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/ajim.22871

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Webber, M. P., Liu, Y., Cohen, H. W., Schwartz, T., Weiden, M. D., Kelly, K., Ortiz, V., Zeig-Owens, R., Jaber, N., Colbeth, H. L., & Prezant, D. J. (2018). Incidence and prevalence of antibody to hepatitis C virus in FDNY first responders before and after work at the World Trade Center disaster site. American Journal of Industrial Medicine, 61(9), 733-740. https://doi.org/10.1002/ajim.22871

Webber, MP, Liu, Y, Cohen, HW, Schwartz, T, Weiden, MD, Kelly, K, Ortiz, V, Zeig-Owens, R, Jaber, N, Colbeth, HL & Prezant, DJ 2018, 'Incidence and prevalence of antibody to hepatitis C virus in FDNY first responders before and after work at the World Trade Center disaster site', American Journal of Industrial Medicine, vol. 61, no. 9, pp. 733-740. https://doi.org/10.1002/ajim.22871

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abstract = "Background: The goals of this study were to assess the impact of work at the World Trade Center (WTC) site in relation to new, post-9/11/2001 (9/11) antibody to hepatitis C Virus (anti-HCV); and, evaluate secular trends in WTC-exposed male Fire Department of New York City (FDNY) Firefighters and Emergency Medical Services (EMS) responders. Methods: FDNY monitors responder health through physical exams and routine blood work. We used descriptive statistics to compare trans-9/11 and post-9/11 incidence and to assess trends in prevalence from 2000 to 2012. Results: Trans-9/11 incidence of new anti-HCV was 0.42 per 100 persons compared with post-9/11 incidence of 0.34 (P = 0.68). Overall seroprevalence was 1.3%; rates declined from 1.79 per 100 to 0.49 per 100 over time (P < 0.0001). Conclusions: Work at the WTC was not associated with new infection. Biennial seroprevalence in responders declined over time, supporting the FDNY decision to discontinue routine annual testing in this cohort.",

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author = "Webber, {Mayris P.} and Yang Liu and Cohen, {Hillel W.} and Theresa Schwartz and Weiden, {Michael D.} and Kerry Kelly and Viola Ortiz and Rachel Zeig-Owens and Nadia Jaber and Colbeth, {Hilary L.} and Prezant, {David J.}",

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doi = "10.1002/ajim.22871",

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AU - Schwartz, Theresa

AU - Weiden, Michael D.

AU - Kelly, Kerry

AU - Ortiz, Viola

AU - Zeig-Owens, Rachel

AU - Jaber, Nadia

AU - Colbeth, Hilary L.

AU - Prezant, David J.

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N2 - Background: The goals of this study were to assess the impact of work at the World Trade Center (WTC) site in relation to new, post-9/11/2001 (9/11) antibody to hepatitis C Virus (anti-HCV); and, evaluate secular trends in WTC-exposed male Fire Department of New York City (FDNY) Firefighters and Emergency Medical Services (EMS) responders. Methods: FDNY monitors responder health through physical exams and routine blood work. We used descriptive statistics to compare trans-9/11 and post-9/11 incidence and to assess trends in prevalence from 2000 to 2012. Results: Trans-9/11 incidence of new anti-HCV was 0.42 per 100 persons compared with post-9/11 incidence of 0.34 (P = 0.68). Overall seroprevalence was 1.3%; rates declined from 1.79 per 100 to 0.49 per 100 over time (P < 0.0001). Conclusions: Work at the WTC was not associated with new infection. Biennial seroprevalence in responders declined over time, supporting the FDNY decision to discontinue routine annual testing in this cohort.

AB - Background: The goals of this study were to assess the impact of work at the World Trade Center (WTC) site in relation to new, post-9/11/2001 (9/11) antibody to hepatitis C Virus (anti-HCV); and, evaluate secular trends in WTC-exposed male Fire Department of New York City (FDNY) Firefighters and Emergency Medical Services (EMS) responders. Methods: FDNY monitors responder health through physical exams and routine blood work. We used descriptive statistics to compare trans-9/11 and post-9/11 incidence and to assess trends in prevalence from 2000 to 2012. Results: Trans-9/11 incidence of new anti-HCV was 0.42 per 100 persons compared with post-9/11 incidence of 0.34 (P = 0.68). Overall seroprevalence was 1.3%; rates declined from 1.79 per 100 to 0.49 per 100 over time (P < 0.0001). Conclusions: Work at the WTC was not associated with new infection. Biennial seroprevalence in responders declined over time, supporting the FDNY decision to discontinue routine annual testing in this cohort.

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Incidence and prevalence of antibody to hepatitis C virus in FDNY first responders before and after work at the World Trade Center disaster site

Abstract

Keywords

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UN SDGs

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