Immune complex-mediated renal involvement in relapsing polychondritis

Luis R. Espinoza; Alan Richman; Tomas Bocanegra; Iliana Pina; Frank B. Vasey; Stephen I. Rifkin; Bernard F. Germain

doi:10.1016/0002-9343(81)90291-6

Immune complex-mediated renal involvement in relapsing polychondritis

Luis R. Espinoza, Alan Richman, Tomas Bocanegra, Iliana Pina, Frank B. Vasey, Stephen I. Rifkin, Bernard F. Germain

Medicine

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18 Scopus citations

Abstract

A patient with relapsing polychondritis who presented with rapidly progressive glomerulonephritis is described. This is the fourth case in which this association is reported. Crescentic glomerulonephritis was found on renal biopsy. Evidence for immunologic participation in the pathogenesis of this condition is suggested by the demonstration of circulating immune complexes, immunoglobulin and complement deposition by immunofluorescence, and electron dense deposits by electron microscopy of the kidney. Favorable response followed therapy with prednisone and dapsone.

Original language	English (US)
Pages (from-to)	181-183
Number of pages	3
Journal	The American Journal of Medicine
Volume	71
Issue number	1
DOIs	https://doi.org/10.1016/0002-9343(81)90291-6
State	Published - Jul 1981

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title = "Immune complex-mediated renal involvement in relapsing polychondritis",

abstract = "A patient with relapsing polychondritis who presented with rapidly progressive glomerulonephritis is described. This is the fourth case in which this association is reported. Crescentic glomerulonephritis was found on renal biopsy. Evidence for immunologic participation in the pathogenesis of this condition is suggested by the demonstration of circulating immune complexes, immunoglobulin and complement deposition by immunofluorescence, and electron dense deposits by electron microscopy of the kidney. Favorable response followed therapy with prednisone and dapsone.",

author = "Espinoza, {Luis R.} and Alan Richman and Tomas Bocanegra and Iliana Pina and Vasey, {Frank B.} and Rifkin, {Stephen I.} and Germain, {Bernard F.}",

year = "1981",

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AU - Espinoza, Luis R.

AU - Richman, Alan

AU - Bocanegra, Tomas

AU - Pina, Iliana

AU - Vasey, Frank B.

AU - Rifkin, Stephen I.

AU - Germain, Bernard F.

PY - 1981/7

Y1 - 1981/7

N2 - A patient with relapsing polychondritis who presented with rapidly progressive glomerulonephritis is described. This is the fourth case in which this association is reported. Crescentic glomerulonephritis was found on renal biopsy. Evidence for immunologic participation in the pathogenesis of this condition is suggested by the demonstration of circulating immune complexes, immunoglobulin and complement deposition by immunofluorescence, and electron dense deposits by electron microscopy of the kidney. Favorable response followed therapy with prednisone and dapsone.

AB - A patient with relapsing polychondritis who presented with rapidly progressive glomerulonephritis is described. This is the fourth case in which this association is reported. Crescentic glomerulonephritis was found on renal biopsy. Evidence for immunologic participation in the pathogenesis of this condition is suggested by the demonstration of circulating immune complexes, immunoglobulin and complement deposition by immunofluorescence, and electron dense deposits by electron microscopy of the kidney. Favorable response followed therapy with prednisone and dapsone.

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JF - American Journal of Medicine

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Immune complex-mediated renal involvement in relapsing polychondritis

Abstract

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