@article{ad754e6270374fa0b39b77835c7d5c6d,
title = "“Hypothalamic Microinflammation” Paradigm in Aging and Metabolic Diseases",
abstract = "The hypothalamus of the brain can become inflamed during aging and in metabolic diseases. In this Perspective, Cai and Khor provide an overview of the mediators, signaling components, and physiological impact of hypothalamic microinflammation. They draw parallels between aging and the metabolic syndrome and highlight important questions to be addressed.",
keywords = "NF-kB, aging, brain, diabetes, hypertension, hypothalamus, inflammation, nuclear factor kappa B, obesity",
author = "Dongsheng Cai and Sinan Khor",
note = "Funding Information: The authors sincerely thank all previous and current lab members for contributions to this research. The research of the authors was supported by Einstein institutional fund and NIH DK078750, AG031774, HL113180, DK099136, HL147477, and DK121435 (all to D.C.). S.K. was partly supported by NIH training grant T32 AG 23475. Funding Information: The authors sincerely thank all previous and current lab members for contributions to this research. The research of the authors was supported by Einstein institutional fund and NIH DK078750 , AG031774 , HL113180 , DK099136 , HL147477 , and DK121435 (all to D.C.). S.K. was partly supported by NIH training grant T32 AG 23475 . Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",
year = "2019",
month = jul,
day = "2",
doi = "10.1016/j.cmet.2019.05.021",
language = "English (US)",
volume = "30",
pages = "19--35",
journal = "Cell metabolism",
issn = "1550-4131",
publisher = "Cell Press",
number = "1",
}
