How many are we missing with ID NOW COVID-19 assay using direct nasopharyngeal swabs? Findings from a mid-sized academic hospital clinical microbiology laboratory

Phyu M. Thwe; Ping Ren

doi:10.1016/j.diagmicrobio.2020.115123

How many are we missing with ID NOW COVID-19 assay using direct nasopharyngeal swabs? Findings from a mid-sized academic hospital clinical microbiology laboratory

Phyu M. Thwe
, Ping Ren

Research output: Contribution to journal › Editorial › peer-review

35 Scopus citations

Abstract

Here, we retrospectively analyzed the comparative results of 182 paired dry nasopharyngeal swabs tested by Abbott ID NOW and nasopharyngeal swabs in viral transport medium by real-time RT-PCR methods. While the overall agreement was 96.2%, we found that of 15 samples that were tested positive with RT-PCR methods, 7 were missed by ID NOW, resulting in a false-negative rate of 47%.

Original language	English (US)
Article number	115123
Journal	Diagnostic Microbiology and Infectious Disease
Volume	98
Issue number	2
DOIs	https://doi.org/10.1016/j.diagmicrobio.2020.115123
State	Published - Oct 2020
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

COVID-19, Abbott ID NOW
Dry nasopharyngeal swab
SARS-CoV-2

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1016/j.diagmicrobio.2020.115123

Cite this

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title = "How many are we missing with ID NOW COVID-19 assay using direct nasopharyngeal swabs? Findings from a mid-sized academic hospital clinical microbiology laboratory",

abstract = "Here, we retrospectively analyzed the comparative results of 182 paired dry nasopharyngeal swabs tested by Abbott ID NOW and nasopharyngeal swabs in viral transport medium by real-time RT-PCR methods. While the overall agreement was 96.2\%, we found that of 15 samples that were tested positive with RT-PCR methods, 7 were missed by ID NOW, resulting in a false-negative rate of 47\%.",

keywords = "COVID-19, Abbott ID NOW, Dry nasopharyngeal swab, SARS-CoV-2",

author = "Thwe, \{Phyu M.\} and Ping Ren",

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AU - Ren, Ping

PY - 2020/10

Y1 - 2020/10

N2 - Here, we retrospectively analyzed the comparative results of 182 paired dry nasopharyngeal swabs tested by Abbott ID NOW and nasopharyngeal swabs in viral transport medium by real-time RT-PCR methods. While the overall agreement was 96.2%, we found that of 15 samples that were tested positive with RT-PCR methods, 7 were missed by ID NOW, resulting in a false-negative rate of 47%.

AB - Here, we retrospectively analyzed the comparative results of 182 paired dry nasopharyngeal swabs tested by Abbott ID NOW and nasopharyngeal swabs in viral transport medium by real-time RT-PCR methods. While the overall agreement was 96.2%, we found that of 15 samples that were tested positive with RT-PCR methods, 7 were missed by ID NOW, resulting in a false-negative rate of 47%.

KW - COVID-19, Abbott ID NOW

KW - Dry nasopharyngeal swab

KW - SARS-CoV-2

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DO - 10.1016/j.diagmicrobio.2020.115123

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How many are we missing with ID NOW COVID-19 assay using direct nasopharyngeal swabs? Findings from a mid-sized academic hospital clinical microbiology laboratory

Abstract

UN SDGs

Keywords

ASJC Scopus subject areas

Access to Document

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