Histoplasma virulence and host responses

Mircea Radu Mihu; Joshua Daniel Nosanchuk

doi:10.1155/2012/268123

Histoplasma virulence and host responses

Mircea Radu Mihu, Joshua Daniel Nosanchuk

Medicine

Research output: Contribution to journal › Review article › peer-review

35 Scopus citations

Abstract

Histoplasma capsulatum is the most prevalent cause of fungal respiratory disease. The disease extent and outcomes are the result of the complex interaction between the pathogen and a host's immune system. The focus of our paper consists in presenting the current knowledge regarding the multiple facets of the dynamic host-pathogen relationship in the context of the virulence arsenal displayed by the fungus and the innate and adaptive immune responses of the host.

Original language	English (US)
Article number	268123
Journal	International Journal of Microbiology
DOIs	https://doi.org/10.1155/2012/268123
State	Published - 2012

ASJC Scopus subject areas

Microbiology
Microbiology (medical)

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title = "Histoplasma virulence and host responses",

abstract = "Histoplasma capsulatum is the most prevalent cause of fungal respiratory disease. The disease extent and outcomes are the result of the complex interaction between the pathogen and a host's immune system. The focus of our paper consists in presenting the current knowledge regarding the multiple facets of the dynamic host-pathogen relationship in the context of the virulence arsenal displayed by the fungus and the innate and adaptive immune responses of the host.",

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year = "2012",

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AU - Nosanchuk, Joshua Daniel

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AB - Histoplasma capsulatum is the most prevalent cause of fungal respiratory disease. The disease extent and outcomes are the result of the complex interaction between the pathogen and a host's immune system. The focus of our paper consists in presenting the current knowledge regarding the multiple facets of the dynamic host-pathogen relationship in the context of the virulence arsenal displayed by the fungus and the innate and adaptive immune responses of the host.

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DO - 10.1155/2012/268123

M3 - Review article

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SN - 1687-918X

JO - International Journal of Microbiology

JF - International Journal of Microbiology

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Histoplasma virulence and host responses

Abstract

ASJC Scopus subject areas

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