Histoplasma virulence and host responses

Mircea Radu Mihu, Joshua Daniel Nosanchuk

Research output: Contribution to journalReview articlepeer-review

31 Scopus citations


Histoplasma capsulatum is the most prevalent cause of fungal respiratory disease. The disease extent and outcomes are the result of the complex interaction between the pathogen and a host's immune system. The focus of our paper consists in presenting the current knowledge regarding the multiple facets of the dynamic host-pathogen relationship in the context of the virulence arsenal displayed by the fungus and the innate and adaptive immune responses of the host.

Original languageEnglish (US)
Article number268123
JournalInternational Journal of Microbiology
StatePublished - 2012

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)


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