Gynaecologic effects of Tamoxifen

Dennis Yi Shin Kuo; Carolyn D. Runowicz

doi:10.1007/BF01676708

Gynaecologic effects of Tamoxifen

Dennis Yi Shin Kuo, Carolyn D. Runowicz

Obstetrics & Gynecology and Women's Health

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Tamoxifen, an estrogen antagonist, is widely used as adjuvant therapy in patients with breast cancer. Its efficacy in increasing survival and reducing recurrence rates has been demonstrated in several European and American studies. However, its effects appear to be tissue specific. Tamoxifen exerts an estrogen effect (agonist) on the endometrium, myometrium and vagina. An increase in uterine cancer has been confirmed in several placebo-controlled clinical trials. Due to the widespread use of this drug, it is timely to review the gynecologic effects of tamoxifen.

Original language	English (US)
Pages (from-to)	87-94
Number of pages	8
Journal	Medical Oncology
Volume	12
Issue number	2
DOIs	https://doi.org/10.1007/BF01676708
State	Published - Jun 1 1995

Keywords

breast cancer
estrogen effect
tamoxifen
uterine cancer

ASJC Scopus subject areas

Hematology
Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/BF01676708

Cite this

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Gynaecologic effects of Tamoxifen

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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