TY - JOUR
T1 - Growth-dependent expression of a cell surface glycoprotein
AU - Theilmann, Lorenz
AU - Teicher, Lucy
AU - Schildkraut, Carl S.
AU - Stockert, Richard J.
PY - 1983/6/2
Y1 - 1983/6/2
N2 - The expression of the hepatocellular membrane receptor for desialylated galactose-termining glycoproteins was studied during different proliferative stages of a human hepatoma cell line. Rapidly growing cells exhibited a reduced endocytotic rate of desialylated orsomucoid as compared to non-growing cells. This reduction was shown to be the consequence of a lower concentration of active cell-surface associated receptor protein in the dividing cells.
AB - The expression of the hepatocellular membrane receptor for desialylated galactose-termining glycoproteins was studied during different proliferative stages of a human hepatoma cell line. Rapidly growing cells exhibited a reduced endocytotic rate of desialylated orsomucoid as compared to non-growing cells. This reduction was shown to be the consequence of a lower concentration of active cell-surface associated receptor protein in the dividing cells.
KW - (Hepatoma cell)
KW - Cell surface
KW - Glycoprotein expression
KW - Growth dependence
UR - http://www.scopus.com/inward/record.url?scp=0020526956&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0020526956&partnerID=8YFLogxK
U2 - 10.1016/0167-4889(83)90015-0
DO - 10.1016/0167-4889(83)90015-0
M3 - Article
C2 - 6303445
AN - SCOPUS:0020526956
SN - 0167-4889
VL - 762
SP - 475
EP - 477
JO - BBA - Molecular Cell Research
JF - BBA - Molecular Cell Research
IS - 3
ER -