Glycosylated hemoglobin level may predict the severity of gastroparesis in diabetic patients

Manhal Izzy, Mindy Lee, Krysta Johns-Keating, Faraj Kargoli, Steven Beckoff, Kwang J. Chun, Aaron Zev Tokayer

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Aim To investigate the association between glycemic control represented by glycated hemoglobin (HbA1c) level and the value of 4-h gastric retention on nuclear scan. Methods We retrospectively reviewed records of diabetic patients who had 4-h nuclear gastric emptying study, with documented 4-h retention value, between January 1st, 2002 and July 30th, 2014 and had HbA1C level close to the time of the study. We divided our cohort into patients with good glycemic control (HbA1C <7, group A), fair control (7–9, group B), and poor control (>9, group C). The 4-h retention value and symptoms were compared between the 3 groups. Results Our cohort included 299 patients; mean age was 59 ± 14. The median interval between performing gastric emptying study and measuring HbA1C was 41 days. There were 94 patients in group A (HbA1C 6.1 ± 0.4), 131 patients in group B (HbA1C 7.9 ± 0.5), and 74 patients in group C (HbA1C 10.9 ± 1.6). The mean gastric retention value was different between the three study groups, 8.3% ±17, 11.5% ±19, and 14.4% ±21, respectively (P = .03). Conclusion This is the first study to show that HbA1C level is significantly associated with the 4-h retention value on nuclear gastric emptying scan.

Original languageEnglish (US)
Pages (from-to)45-49
Number of pages5
JournalDiabetes Research and Clinical Practice
StatePublished - Jan 1 2018


  • Gastric dysmotility
  • Gastric emptying study
  • Gastroparesis
  • Glycated hemoglobin

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology


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