Getting to synaptic complexes through systems biology

Bryen A. Jordan; Edward B. Ziff

doi:10.1186/gb-2006-7-4-214

Getting to synaptic complexes through systems biology

Bryen A. Jordan, Edward B. Ziff

Research output: Contribution to journal › Short survey › peer-review

5 Scopus citations

Abstract

Large numbers of synaptic components have been identified, but the effect so far on our understanding of synaptic function is limited. Now, network maps and annotated functions of individual components have been used in a systems biology approach to analyzing the function of NMDA receptor complexes at synapses, identifying biologically relevant modular networks within the complex.

Original language	English (US)
Article number	214
Journal	Genome biology
Volume	7
Issue number	4
DOIs	https://doi.org/10.1186/gb-2006-7-4-214
State	Published - Apr 27 2006
Externally published	Yes

ASJC Scopus subject areas

Ecology, Evolution, Behavior and Systematics
Genetics
Cell Biology

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10.1186/gb-2006-7-4-214

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title = "Getting to synaptic complexes through systems biology",

abstract = "Large numbers of synaptic components have been identified, but the effect so far on our understanding of synaptic function is limited. Now, network maps and annotated functions of individual components have been used in a systems biology approach to analyzing the function of NMDA receptor complexes at synapses, identifying biologically relevant modular networks within the complex.",

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year = "2006",

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AU - Jordan, Bryen A.

AU - Ziff, Edward B.

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AB - Large numbers of synaptic components have been identified, but the effect so far on our understanding of synaptic function is limited. Now, network maps and annotated functions of individual components have been used in a systems biology approach to analyzing the function of NMDA receptor complexes at synapses, identifying biologically relevant modular networks within the complex.

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DO - 10.1186/gb-2006-7-4-214

M3 - Short survey

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SN - 1474-760X

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JO - Genome biology

JF - Genome biology

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Getting to synaptic complexes through systems biology

Abstract

ASJC Scopus subject areas

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