Gαs Uncouples Hematopoietic Stem Cell Homing and Mobilization

Simón Méndez-Ferrer; Paul S. Frenette

doi:10.1016/j.stem.2009.04.009

Gα_s Uncouples Hematopoietic Stem Cell Homing and Mobilization

Simón Méndez-Ferrer
, Paul S. Frenette

Research output: Contribution to journal › Short survey › peer-review

10 Scopus citations

Abstract

Defects of hematopoietic stem cell adhesion or migration generally lead to reduced homing to, and enhanced mobilization from, the bone marrow. In a recent publication in Nature, Adams et al. (2009) demonstrate that the guanine-nucleotide-binding stimulatory α subunit (Gα_s) can, unexpectedly, promote both phenomena.

Original language	English (US)
Pages (from-to)	379-380
Number of pages	2
Journal	Cell Stem Cell
Volume	4
Issue number	5
DOIs	https://doi.org/10.1016/j.stem.2009.04.009
State	Published - May 8 2009
Externally published	Yes

ASJC Scopus subject areas

Molecular Medicine
Genetics
Cell Biology

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10.1016/j.stem.2009.04.009

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@article{e55c981561ec4bbda1ac767c6a58e497,

title = "Gαs Uncouples Hematopoietic Stem Cell Homing and Mobilization",

abstract = "Defects of hematopoietic stem cell adhesion or migration generally lead to reduced homing to, and enhanced mobilization from, the bone marrow. In a recent publication in Nature, Adams et al. (2009) demonstrate that the guanine-nucleotide-binding stimulatory α subunit (Gαs) can, unexpectedly, promote both phenomena.",

author = "Sim{\'o}n M{\'e}ndez-Ferrer and Frenette, \{Paul S.\}",

year = "2009",

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day = "8",

doi = "10.1016/j.stem.2009.04.009",

language = "English (US)",

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journal = "Cell Stem Cell",

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T1 - Gαs Uncouples Hematopoietic Stem Cell Homing and Mobilization

AU - Méndez-Ferrer, Simón

AU - Frenette, Paul S.

PY - 2009/5/8

Y1 - 2009/5/8

N2 - Defects of hematopoietic stem cell adhesion or migration generally lead to reduced homing to, and enhanced mobilization from, the bone marrow. In a recent publication in Nature, Adams et al. (2009) demonstrate that the guanine-nucleotide-binding stimulatory α subunit (Gαs) can, unexpectedly, promote both phenomena.

AB - Defects of hematopoietic stem cell adhesion or migration generally lead to reduced homing to, and enhanced mobilization from, the bone marrow. In a recent publication in Nature, Adams et al. (2009) demonstrate that the guanine-nucleotide-binding stimulatory α subunit (Gαs) can, unexpectedly, promote both phenomena.

UR - https://www.scopus.com/pages/publications/65349148444

UR - https://www.scopus.com/pages/publications/65349148444#tab=citedBy

U2 - 10.1016/j.stem.2009.04.009

DO - 10.1016/j.stem.2009.04.009

M3 - Short survey

C2 - 19427288

AN - SCOPUS:65349148444

SN - 1934-5909

VL - 4

SP - 379

EP - 380

JO - Cell Stem Cell

JF - Cell Stem Cell

IS - 5

ER -

Gα_s Uncouples Hematopoietic Stem Cell Homing and Mobilization

Abstract

ASJC Scopus subject areas

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