TY - JOUR
T1 - Future Perspectives in Percutaneous Treatment of Tricuspid Regurgitation
AU - Mangieri, Antonio
AU - Pagnesi, Matteo
AU - Regazzoli, Damiano
AU - Laricchia, Alessandra
AU - Ho, Edwin
AU - Goldberg, Ythan
AU - Chau, Mei
AU - Gallo, Francesco
AU - Fisicaro, Andrea
AU - Khokhar, Arif
AU - Colombo, Antonio
AU - Giannini, Francesco
AU - Latib, Azeem
N1 - Publisher Copyright:
© Copyright © 2020 Mangieri, Pagnesi, Regazzoli, Laricchia, Ho, Goldberg, Chau, Gallo, Fisicaro, Khokhar, Colombo, Giannini and Latib.
PY - 2020/10/14
Y1 - 2020/10/14
N2 - Tricuspid regurgitation (TR) has a not negligible prevalence and its severity is correlated with poorer outcomes. However, surgical options are rarely offered to these patients because of their high surgical risk. Given that medical therapy plays a limited role in the management of these patients, there is an increasing clinical need for transcatheter treatment options. Although, transcatheter tricuspid valve interventions (TTVIs) are still at an early stage, emerging data suggests their clinical effectiveness and safety, with preliminary results highlighting the potential benefits of transcatheter treatments over medical therapy. In this review, we highlight the challenges and future directions of current and emerging technologies dedicated to the treatment of TR along with an analysis of the next steps required in future clinical trials and studies dedicated to the treatment of the forgotten valve.
AB - Tricuspid regurgitation (TR) has a not negligible prevalence and its severity is correlated with poorer outcomes. However, surgical options are rarely offered to these patients because of their high surgical risk. Given that medical therapy plays a limited role in the management of these patients, there is an increasing clinical need for transcatheter treatment options. Although, transcatheter tricuspid valve interventions (TTVIs) are still at an early stage, emerging data suggests their clinical effectiveness and safety, with preliminary results highlighting the potential benefits of transcatheter treatments over medical therapy. In this review, we highlight the challenges and future directions of current and emerging technologies dedicated to the treatment of TR along with an analysis of the next steps required in future clinical trials and studies dedicated to the treatment of the forgotten valve.
KW - intracardiac echocardiography
KW - transcatheter tricuspid valve intervention
KW - transcatheter tricuspid valve replacement
KW - transesophageal echocardiography
KW - tricuspid regurgitation
KW - tricuspid valve
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U2 - 10.3389/fcvm.2020.581211
DO - 10.3389/fcvm.2020.581211
M3 - Review article
AN - SCOPUS:85107267720
SN - 2297-055X
VL - 7
JO - Frontiers in Cardiovascular Medicine
JF - Frontiers in Cardiovascular Medicine
M1 - 581211
ER -