Fibrillogenesis of tau: Insights from Tau missense mutations in FTDP-17

Keyphrases

• Missense mutation 100%
• Fibrillogenesis 100%
• FTDP-17 100%
• 5′ Splice Site 50%
• Tau Filaments 50%
• Exon 10 50%
• Tau Gene 50%
• Neurological Disorders 25%
• Transfected Cells 25%
• Tau Pathology 25%
• Frontotemporal Dementia 25%
• Elongation Phase 25%
• Heparin 25%
• Chromosome 17 25%
• Gene mutation 25%
• Polymerized 25%
• COS-7 Cells 25%
• Parkinsonism 25%
• Filament Formation 25%
• Phosphorylation 25%
• Cell Surface Display 25%
• 4R tau 25%
• Tau mutation 25%
• Tau Isoforms 25%
• Tau Deposits 25%
• Exon 9 25%
• Cultured Cells 25%
• 3R tau 25%
• Arachidonic Acid 25%
• Extent of Reduction 25%
• Cell Changes 25%
• Tubulin 25%
• Inducing Agents 25%
• Alternative Splicing 25%
• Nucleation Phase 25%
• Phosphorylated tau 25%
• Microtubule Assembly 25%
• Number of mutations 25%
• R406W 25%
• Splice Site mutation 25%

Neuroscience

• Missense Mutation 100%
• Exon 100%
• Microtubule Assembly 33%
• In Vitro 33%
• Heparin 33%
• Frontotemporal Dementia 33%
• Parkinsonism 33%
• Tubulin 33%
• Arachidonic Acid 33%
• Gene Mutation 33%
• Alternative Splicing 33%
• Chromosome 17 33%
• Nervous System Disorder 33%
• phosphorylation 33%

Biochemistry, Genetics and Molecular Biology

• Missense Mutation 100%
• Tau 100%
• Fibrillogenesis 100%
• Exon 16%
• Tubulin 5%
• Chromosome 17 5%
• Isoform 5%
• Heparin 5%
• Wild Type 5%
• Microtubule Assembly 5%
• Alternative Splicing 5%
• Gene Mutation 5%
• Splice Site Mutation 5%
• Arachidonic Acid 5%
• phosphorylation 5%