Eyelid syringocystadenoma papilliferum: A novel presentation with major review

Michael C. Tseng, Bijal Amin, Anne Barmettler

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


A major review of the literature of syringocystadenoma papilliferum’s (SCAP’s) presentation and management is presented. In addition, a case report of this unique diagnosis presenting as a corneal abrasion in a 66-year-old-male is included. This benign adnexal tumor of the apocrine glands is most commonly found in the face and neck. When found on the eyelids, these lesions are commonly misdiagnosed as basal cell carcinoma or cysts. Diagnosis is made based on histopathology. Treatment is complete excision of the lesion and this has a low recurrence rate. While predominantly benign, there have been cases of basal cell carcinoma development or other malignant transformations. Of the 26 reported cases of SCAP of the eyelids, none have caused a corneal abrasion. The authors present the only known presentation of eyelid SCAP, causing corneal abrasions, and provide a review of literature with discussion of clinical presentation, natural history, diagnosis, and treatment of this rare, eyelid lesion with potential for malignant transformation.

Original languageEnglish (US)
Pages (from-to)171-174
Number of pages4
JournalOrbit (London)
Issue number3
StatePublished - May 4 2018


  • Apocrine
  • Syringocystadenoma papilliferum
  • eyelid
  • review

ASJC Scopus subject areas

  • Ophthalmology


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