Ewing's sarcoma in a patient with congenital optic atrophy

Carolyn Fein-Levy, Richard Gorlick, Paul A. Meyers, John Healey, Andrew G. Huvos

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Purpose: The authors report Ewing's sarcoma in a patient with congenital optic atrophy. Congenital optic atrophy is an autosomal dominant disorder with variable expression. It manifests itself within the first decade of life and is accompanied by changes in visual acuity. This condition has not been known to cause a predisposition toward malignancy. Patient and Methods: In this article, a 16-year-old girl with dominant optic atrophy and Ewing's sarcoma is described. Results: After tumor resection, the patient was successfully treated for Ewing's sarcoma with chemotherapy and radiation therapy. Today she has no evidence of malignancy. However, she continues to have deterioration of her visual acuity. Conclusion: This report of cancer in a child with dominant optic atrophy suggests the possible need for a higher degree of suspicion of malignancy in these patients.

Original languageEnglish (US)
Pages (from-to)577-579
Number of pages3
JournalJournal of Pediatric Hematology/Oncology
Issue number6
StatePublished - 1998
Externally publishedYes


  • Case report
  • Congenital optic atrophy
  • Ewing's sarcoma

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology


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