Evolution and sequence analysis of a human Y-chromosomal DNA fragment

E. C. Whisenant; B. K.A. Rasheed; H. Ostrer; Y. M. Bhatnagar

doi:10.1007/BF02193627

Evolution and sequence analysis of a human Y-chromosomal DNA fragment

E. C. Whisenant, B. K.A. Rasheed, H. Ostrer, Y. M. Bhatnagar

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

A Y-chromosomal DNA fragment has been isolated from a human Y-Charon 21A recombinant library. Evolutionary analysis of 1F5 indicates that the size and sequence of this fragment have been conserved in higher primates. Deletion mapping and in situ hybridization analysis have localized 1F5 to the middle euchromatic portion of the long arm of the human Y chromosome at Yq11.2. Sequence analysis revealed the presence of an atypical Alu element and two regions rich in polypyrimidine-polypurine residues.

Original language	English (US)
Pages (from-to)	133-141
Number of pages	9
Journal	Journal of Molecular Evolution
Volume	33
Issue number	2
DOIs	https://doi.org/10.1007/BF02193627
State	Published - Aug 1 1991
Externally published	Yes

Keywords

Alu element
DNA
Evolution
Human
PUPPY sequence
Primate
Y-chromosome

ASJC Scopus subject areas

Ecology, Evolution, Behavior and Systematics
Molecular Biology
Genetics

Access to Document

10.1007/BF02193627

Cite this

@article{bf725650874543d6a554ba23556d3970,

title = "Evolution and sequence analysis of a human Y-chromosomal DNA fragment",

abstract = "A Y-chromosomal DNA fragment has been isolated from a human Y-Charon 21A recombinant library. Evolutionary analysis of 1F5 indicates that the size and sequence of this fragment have been conserved in higher primates. Deletion mapping and in situ hybridization analysis have localized 1F5 to the middle euchromatic portion of the long arm of the human Y chromosome at Yq11.2. Sequence analysis revealed the presence of an atypical Alu element and two regions rich in polypyrimidine-polypurine residues.",

keywords = "Alu element, DNA, Evolution, Human, PUPPY sequence, Primate, Y-chromosome",

author = "Whisenant, {E. C.} and Rasheed, {B. K.A.} and H. Ostrer and Bhatnagar, {Y. M.}",

year = "1991",

month = aug,

day = "1",

doi = "10.1007/BF02193627",

language = "English (US)",

volume = "33",

pages = "133--141",

journal = "Journal of Molecular Evolution",

issn = "0022-2844",

publisher = "Springer New York",

number = "2",

}

TY - JOUR

T1 - Evolution and sequence analysis of a human Y-chromosomal DNA fragment

AU - Whisenant, E. C.

AU - Rasheed, B. K.A.

AU - Ostrer, H.

AU - Bhatnagar, Y. M.

PY - 1991/8/1

Y1 - 1991/8/1

N2 - A Y-chromosomal DNA fragment has been isolated from a human Y-Charon 21A recombinant library. Evolutionary analysis of 1F5 indicates that the size and sequence of this fragment have been conserved in higher primates. Deletion mapping and in situ hybridization analysis have localized 1F5 to the middle euchromatic portion of the long arm of the human Y chromosome at Yq11.2. Sequence analysis revealed the presence of an atypical Alu element and two regions rich in polypyrimidine-polypurine residues.

AB - A Y-chromosomal DNA fragment has been isolated from a human Y-Charon 21A recombinant library. Evolutionary analysis of 1F5 indicates that the size and sequence of this fragment have been conserved in higher primates. Deletion mapping and in situ hybridization analysis have localized 1F5 to the middle euchromatic portion of the long arm of the human Y chromosome at Yq11.2. Sequence analysis revealed the presence of an atypical Alu element and two regions rich in polypyrimidine-polypurine residues.

KW - Alu element

KW - DNA

KW - Evolution

KW - Human

KW - PUPPY sequence

KW - Primate

KW - Y-chromosome

UR - http://www.scopus.com/inward/record.url?scp=0026009162&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026009162&partnerID=8YFLogxK

U2 - 10.1007/BF02193627

DO - 10.1007/BF02193627

M3 - Article

C2 - 1920449

AN - SCOPUS:0026009162

SN - 0022-2844

VL - 33

SP - 133

EP - 141

JO - Journal of Molecular Evolution

JF - Journal of Molecular Evolution

IS - 2

ER -

Evolution and sequence analysis of a human Y-chromosomal DNA fragment

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this