Evaluation of the cardiac chambers on axial CT: Comparison with echocardiography

Rohit Ramanathan, Anil K. Anumandla, Linda B. Haramati, Daniel M. Spevack, Alla Godelman, Vineet R. Jain, Jacob Kazam, William B. Burton, Jeffrey M. Levsky

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


OBJECTIVE: To evaluate qualitative and simple quantitative measures of all 4 cardiac chamber sizes on computed tomography (CT) in comparison with transthoracic echocardiography (TTE). METHODS: We retrospectively identified 104 adults with electrocardiographically gated cardiac CT and TTE within 3 months. Axial early diastolic (75% R-R) CT images were reviewed for qualitative chamber enlargement, and each chamber was measured linearly. Transthoracic echocardiography was reviewed for linear, area, and volume measurements. Interrater agreement was calculated using Cohen κ and Pearson correlation. RESULTS: There were significant correlations between linear left atrium and left ventricle sizes by CT and TTE (r = 0.686 and r = 0.709, respectively). Correlations for right atrium and right ventricle measurements were lower (r = 0.447 and r = 0.492, respectively). Agreement between CT and TTE for qualitative chamber enlargement was poor (highest κ = 0.35). Computed tomography sensitivity was ≤ 62% for enlargement of all chambers. CONCLUSIONS: Linear CT measurements of left-sided chamber sizes correlate well with TTE. Right heart measurements and qualitative assessments agreed poorly with TTE.

Original languageEnglish (US)
Pages (from-to)53-60
Number of pages8
JournalJournal of computer assisted tomography
Issue number1
StatePublished - 2014


  • CT
  • Cardiac chamber sizes
  • Echocardiography
  • Heart size

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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