Epithelial-to-mesenchymal transition of tubular epithelial cells in renal fibrosis: A new twist on an old tale

Madhav C. Menon; Michael J. Ross

doi:10.1016/j.kint.2015.12.025

Epithelial-to-mesenchymal transition of tubular epithelial cells in renal fibrosis: A new twist on an old tale

Madhav C. Menon, Michael J. Ross

Research output: Contribution to journal › Comment/debate › peer-review

25 Scopus citations

Abstract

Recent publications have questioned whether epithelial-to-mesenchymal transition of tubular epithelial cells is an important contributor to renal fibrosis. Two recent publications describe an intratubular epithelial-to-mesenchymal transition-like program of epithelial cell dedifferentiation that may contribute to the recruitment or proliferation of interstitial myofibroblasts after kidney injury.

Original language	English (US)
Pages (from-to)	263-266
Number of pages	4
Journal	Kidney international
Volume	89
Issue number	2
DOIs	https://doi.org/10.1016/j.kint.2015.12.025
State	Published - Feb 1 2016
Externally published	Yes

ASJC Scopus subject areas

Nephrology

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10.1016/j.kint.2015.12.025

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title = "Epithelial-to-mesenchymal transition of tubular epithelial cells in renal fibrosis: A new twist on an old tale",

abstract = "Recent publications have questioned whether epithelial-to-mesenchymal transition of tubular epithelial cells is an important contributor to renal fibrosis. Two recent publications describe an intratubular epithelial-to-mesenchymal transition-like program of epithelial cell dedifferentiation that may contribute to the recruitment or proliferation of interstitial myofibroblasts after kidney injury.",

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AU - Ross, Michael J.

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AB - Recent publications have questioned whether epithelial-to-mesenchymal transition of tubular epithelial cells is an important contributor to renal fibrosis. Two recent publications describe an intratubular epithelial-to-mesenchymal transition-like program of epithelial cell dedifferentiation that may contribute to the recruitment or proliferation of interstitial myofibroblasts after kidney injury.

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Epithelial-to-mesenchymal transition of tubular epithelial cells in renal fibrosis: A new twist on an old tale

Abstract

ASJC Scopus subject areas

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