Epidemiology of Acid-Base Derangements in CKD

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


Acid-base disorders are in patients with chronic kidney disease, with chronic metabolic acidosis receiving the most attention clinically in terms of diagnosis and treatment. A number of observational studies have reported on the prevalence of acid-base disorders in this patient population and their relationship with outcomes, mostly focusing on chronic metabolic acidosis. The majority have used serum bicarbonate alone to define acid-base status due to the lack of widely available data on other acid-base disorders. This review discusses the time course of acid-base alterations in CKD patients, their prevalence, and associations with CKD progression and mortality.

Original languageEnglish (US)
Pages (from-to)280-288
Number of pages9
JournalAdvances in Chronic Kidney Disease
Issue number5
StatePublished - Sep 1 2017


  • Acidosis
  • Alkalosis
  • Epidemiology
  • Mortality
  • Renal insufficiency

ASJC Scopus subject areas

  • Nephrology


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