Enzymic synthesis of deoxyribonucleic acid: XX. Electron microscopy of products primed by native templates

R. B. Inman; C. L. Schildkraut; Arthur Kornberg

doi:10.1016/S0022-2836(65)80058-4

Enzymic synthesis of deoxyribonucleic acid: XX. Electron microscopy of products primed by native templates

R. B. Inman
, C. L. Schildkraut
, Arthur Kornberg

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Native T7 DNA is seen in the electron microscope as a continuous fiber about 11 μ, long, without branches. The product of replication of T7 DNA (and also phage λ DNA) by Escherichia coli polymerase showed, in a large number of the molecules, a branched structure with as many as 12 ends. Branching appears early in the course of replication and persists in the product isolated free from template and enzyme.

Original language	English (US)
Pages (from-to)	285-292
Number of pages	8
Journal	Journal of Molecular Biology
Volume	11
Issue number	2
DOIs	https://doi.org/10.1016/S0022-2836(65)80058-4
State	Published - 1965
Externally published	Yes

ASJC Scopus subject areas

Structural Biology
Molecular Biology

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10.1016/S0022-2836(65)80058-4

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title = "Enzymic synthesis of deoxyribonucleic acid: XX. Electron microscopy of products primed by native templates",

abstract = "Native T7 DNA is seen in the electron microscope as a continuous fiber about 11 μ, long, without branches. The product of replication of T7 DNA (and also phage λ DNA) by Escherichia coli polymerase showed, in a large number of the molecules, a branched structure with as many as 12 ends. Branching appears early in the course of replication and persists in the product isolated free from template and enzyme.",

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year = "1965",

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AU - Inman, R. B.

AU - Schildkraut, C. L.

AU - Kornberg, Arthur

PY - 1965

Y1 - 1965

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AB - Native T7 DNA is seen in the electron microscope as a continuous fiber about 11 μ, long, without branches. The product of replication of T7 DNA (and also phage λ DNA) by Escherichia coli polymerase showed, in a large number of the molecules, a branched structure with as many as 12 ends. Branching appears early in the course of replication and persists in the product isolated free from template and enzyme.

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DO - 10.1016/S0022-2836(65)80058-4

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Enzymic synthesis of deoxyribonucleic acid: XX. Electron microscopy of products primed by native templates

Abstract

ASJC Scopus subject areas

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