Environmental medical epigenetics: A review of epigenetically induced medical risks generated from exposures in our air, food, and personal products

Rachel L. Miller; Jessica Oh

doi:10.1016/B978-0-12-823928-5.00034-7

Environmental medical epigenetics: A review of epigenetically induced medical risks generated from exposures in our air, food, and personal products

Rachel L. Miller, Jessica Oh

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This chapter will cover key concepts related to multiple common environmental exposures such as allergens, pollutants, chemicals, and dietary sources. The chapter will review the latest findings delineating their roles in disease development or exacerbation via epigenetic processes. Recent animal models and human cohort studies demonstrating environmental epigenetic regulation will be stressed, as will the importance of specific time windows of exposure. In general, this review suggests that despite continuing expansion of this field in recent years, many fundamental questions and research gaps remain, particularly those related to understanding the mechanisms that cause chronic diseases and the importance of specific time periods of exposure on epigenetic regulation.

Original language	English (US)
Title of host publication	Medical Epigenetics
Publisher	Elsevier
Pages	51-79
Number of pages	29
ISBN (Electronic)	9780128239285
DOIs	https://doi.org/10.1016/B978-0-12-823928-5.00034-7
State	Published - Jan 1 2021
Externally published	Yes

Keywords

DNA methylation
Environmental epigenetics
Histone modification

ASJC Scopus subject areas

Medicine(all)
Biochemistry, Genetics and Molecular Biology(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/B978-0-12-823928-5.00034-7

Cite this

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abstract = "This chapter will cover key concepts related to multiple common environmental exposures such as allergens, pollutants, chemicals, and dietary sources. The chapter will review the latest findings delineating their roles in disease development or exacerbation via epigenetic processes. Recent animal models and human cohort studies demonstrating environmental epigenetic regulation will be stressed, as will the importance of specific time windows of exposure. In general, this review suggests that despite continuing expansion of this field in recent years, many fundamental questions and research gaps remain, particularly those related to understanding the mechanisms that cause chronic diseases and the importance of specific time periods of exposure on epigenetic regulation.",

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AB - This chapter will cover key concepts related to multiple common environmental exposures such as allergens, pollutants, chemicals, and dietary sources. The chapter will review the latest findings delineating their roles in disease development or exacerbation via epigenetic processes. Recent animal models and human cohort studies demonstrating environmental epigenetic regulation will be stressed, as will the importance of specific time windows of exposure. In general, this review suggests that despite continuing expansion of this field in recent years, many fundamental questions and research gaps remain, particularly those related to understanding the mechanisms that cause chronic diseases and the importance of specific time periods of exposure on epigenetic regulation.

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KW - Histone modification

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M3 - Chapter

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PB - Elsevier

ER -

Environmental medical epigenetics: A review of epigenetically induced medical risks generated from exposures in our air, food, and personal products

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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