Environmental medical epigenetics: A review of epigenetically induced medical risks generated from exposures in our air, food, and personal products

Rachel L. Miller, Jessica Oh

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This chapter will cover key concepts related to multiple common environmental exposures such as allergens, pollutants, chemicals, and dietary sources. The chapter will review the latest findings delineating their roles in disease development or exacerbation via epigenetic processes. Recent animal models and human cohort studies demonstrating environmental epigenetic regulation will be stressed, as will the importance of specific time windows of exposure. In general, this review suggests that despite continuing expansion of this field in recent years, many fundamental questions and research gaps remain, particularly those related to understanding the mechanisms that cause chronic diseases and the importance of specific time periods of exposure on epigenetic regulation.

Original languageEnglish (US)
Title of host publicationMedical Epigenetics
PublisherElsevier
Pages51-79
Number of pages29
ISBN (Electronic)9780128239285
DOIs
StatePublished - Jan 1 2021
Externally publishedYes

Keywords

  • DNA methylation
  • Environmental epigenetics
  • Histone modification

ASJC Scopus subject areas

  • General Medicine
  • General Biochemistry, Genetics and Molecular Biology

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