Electrical Coupling and Neuronal Synchronization in the Mammalian Brain

Michael V.L. Bennett, R. Suzanne Zukin

Research output: Contribution to journalReview articlepeer-review

611 Scopus citations


Certain neurons in the mammalian brain have long been known to be joined by gap junctions, which are the most common type of electrical synapse. More recently, cloning of neuron-specific connexins, increased capability of visualizing cells within brain tissue, labeling of cell types by transgenic methods, and generation of connexin knockouts have spurred a rapid increase in our knowledge of the role of gap junctions in neural activity. This article reviews the many subtleties of transmission mediated by gap junctions and the mechanisms whereby these junctions contribute to synchronous firing.

Original languageEnglish (US)
Pages (from-to)495-511
Number of pages17
Issue number4
StatePublished - Feb 19 2004

ASJC Scopus subject areas

  • Neuroscience(all)


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