Effects of Health Insurance Interruption on Loss of Hypertension Control in Women with and Women Without HIV

Andrew Edmonds, Christina Ludema, Joseph J. Eron, Stephen R. Cole, Adebola A. Adedimeji, Mardge H. Cohen, Hannah L. Cooper, Margaret Fischl, Mallory O. Johnson, Denise D. Krause, Dan Merenstein, Joel Milam, Tracey E. Wilson, Adaora A. Adimora

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Background: Among low-income women with and without HIV, it is a priority to reduce age-related comorbidities, including hypertension and its sequelae. Because consistent health insurance access has been identified as an important factor in controlling many chronic diseases, we estimated the effects of coverage interruption on loss of hypertension control in a cohort of women in the United States. Methods: We analyzed prospective, longitudinal data from the Women's Interagency HIV Study. HIV-infected and HIV-uninfected women were included between 2005 and 2014 when they reported health insurance at consecutive biannual visits and had controlled hypertension, and were followed for any insurance break and loss of hypertension control. We estimated hazard ratios (HRs) by Cox proportional hazards regression with inverse-probability-of-treatment-and censoring weights (marginal structural models), and plotted the cumulative incidence of hypertension control loss. Results: Among 890 HIV-infected women, the weighted HR for hypertension control loss comparing health insurance interruption to uninterrupted coverage was 1.37 (95% confidence interval [CI], 0.99-1.91). Inclusion of AIDS Drug Assistance Program (ADAP) participation with health insurance modestly increased the HR (1.47; 95% CI, 1.04-2.07). Analysis of 272 HIV-uninfected women yielded a similar HR (1.39; 95% CI, 0.88-2.21). Additionally, there were indications of uninterrupted coverage having a protective effect on hypertension when compared with the natural course in HIV-infected (HR, 0.82; 95% CI, 0.61-1.11) and HIV-uninfected (HR, 0.78; 95% CI, 0.52-1.19) women. Conclusions: This study provides evidence that health insurance continuity promotes hypertension control in key populations. Interventions that ensure coverage stability and ADAP access should be a policy priority.

Original languageEnglish (US)
Pages (from-to)1292-1301
Number of pages10
JournalJournal of Women's Health
Issue number12
StatePublished - Dec 2017


  • health insurance
  • hypertension
  • women

ASJC Scopus subject areas

  • Medicine(all)


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