Early seizures following intracerebral hemorrhage: Implications for therapy

A. R. Berger, R. B. Lipton, M. L. Lesser, G. Lantos, R. K. Portenoy

Research output: Contribution to journalArticlepeer-review

149 Scopus citations

Abstract

Seizures occurred in 19 of 112 patients (17%) with nontraumatic, supratentorial intracerebral hemorrhage (ICH). All seizures occurred at ICH onset; patients without seizures at hemorrhage onset remained seizure-free until the last recorded follow-up. Seizures were significantly associated with extension of blood into the cerebral cortex. We found no association between seizures and hemorrhage size or the presence of subarachnoid or intraventricular blood. These data suggest that (1) seizures, in ICH, occur at hemorrhage onset, (2) patients without seizures at hemorrhage onset are at very low risk for subsequent seizures during their hospitalization, (3) hemorrhage involving the cerebral cortex, regardless of site of origin, predisposes to seizures, and (4) the prophylactic use of anticonvulsanta in the acute management of these patients appears unwarranted, especially in patients without cortical extension.

Original languageEnglish (US)
Pages (from-to)1363-1365
Number of pages3
JournalNeurology
Volume38
Issue number9
DOIs
StatePublished - Sep 1988

ASJC Scopus subject areas

  • Clinical Neurology

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