Dynamics of cerebrospinal fluid in the subrachnoid space within spinal cavity

Jifeng Peng; Lili Zheng; Michael Egnor; Mark Wagshul

doi:10.1115/IMECE2003-43835

Dynamics of cerebrospinal fluid in the subrachnoid space within spinal cavity

Jifeng Peng, Lili Zheng, Michael Egnor, Mark Wagshul

Research output: Contribution to journal › Conference article › peer-review

1 Scopus citations

Abstract

In this paper, a computational study was carried out to investigate the CSF dynamics in the spinal cavity. A theoretical and computational model was developed to simulate the pulsatile CSF flow and the deformation of the spinal cavity that results from transmission of the CSF pulse wave from the cranial cavity. Under a pulsatile pressure gradient, the velocity profile of the flow is blunt for large Womersley numbers, while for small Womersley numbers the velocity profile is parabolic. The phase relationship between the pressure and the velocity is also related to Womersley number. This is the first step to understand the pulsatile dynamics of the CSF in the spinal cavity and will help explain the cause of related diseases and improve the clinical treatment.

Original language	English (US)
Pages (from-to)	143-144
Number of pages	2
Journal	American Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Volume	55
DOIs	https://doi.org/10.1115/IMECE2003-43835
State	Published - Jan 1 2003
Externally published	Yes
Event	2003 ASME International Mechanical Engineering Congress - Washington, DC., United States Duration: Nov 15 2003 → Nov 21 2003

ASJC Scopus subject areas

Engineering(all)

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title = "Dynamics of cerebrospinal fluid in the subrachnoid space within spinal cavity",

abstract = "In this paper, a computational study was carried out to investigate the CSF dynamics in the spinal cavity. A theoretical and computational model was developed to simulate the pulsatile CSF flow and the deformation of the spinal cavity that results from transmission of the CSF pulse wave from the cranial cavity. Under a pulsatile pressure gradient, the velocity profile of the flow is blunt for large Womersley numbers, while for small Womersley numbers the velocity profile is parabolic. The phase relationship between the pressure and the velocity is also related to Womersley number. This is the first step to understand the pulsatile dynamics of the CSF in the spinal cavity and will help explain the cause of related diseases and improve the clinical treatment.",

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AU - Peng, Jifeng

AU - Zheng, Lili

AU - Egnor, Michael

AU - Wagshul, Mark

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Y1 - 2003/1/1

N2 - In this paper, a computational study was carried out to investigate the CSF dynamics in the spinal cavity. A theoretical and computational model was developed to simulate the pulsatile CSF flow and the deformation of the spinal cavity that results from transmission of the CSF pulse wave from the cranial cavity. Under a pulsatile pressure gradient, the velocity profile of the flow is blunt for large Womersley numbers, while for small Womersley numbers the velocity profile is parabolic. The phase relationship between the pressure and the velocity is also related to Womersley number. This is the first step to understand the pulsatile dynamics of the CSF in the spinal cavity and will help explain the cause of related diseases and improve the clinical treatment.

AB - In this paper, a computational study was carried out to investigate the CSF dynamics in the spinal cavity. A theoretical and computational model was developed to simulate the pulsatile CSF flow and the deformation of the spinal cavity that results from transmission of the CSF pulse wave from the cranial cavity. Under a pulsatile pressure gradient, the velocity profile of the flow is blunt for large Womersley numbers, while for small Womersley numbers the velocity profile is parabolic. The phase relationship between the pressure and the velocity is also related to Womersley number. This is the first step to understand the pulsatile dynamics of the CSF in the spinal cavity and will help explain the cause of related diseases and improve the clinical treatment.

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JO - American Society of Mechanical Engineers, Bioengineering Division (Publication) BED

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Dynamics of cerebrospinal fluid in the subrachnoid space within spinal cavity

Abstract

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