Does major depressive disorder with somatic delusions constitute a distinct subtype of major depressive disorder with psychotic features?

Taafoi S. Kamara; Ellen M. Whyte; Benoit H. Mulsant; Catherine Peasley-Miklus; Anthony J. Rothschild; Alastair J. Flint; Moonseong Heo; Eros Papademetriou; Erin R. Mathis; Barnett S. Meyers

doi:10.1016/j.jad.2008.04.008

Does major depressive disorder with somatic delusions constitute a distinct subtype of major depressive disorder with psychotic features?

Taafoi S. Kamara, Ellen M. Whyte, Benoit H. Mulsant, Catherine Peasley-Miklus, Anthony J. Rothschild, Alastair J. Flint, Moonseong Heo, Eros Papademetriou, Erin R. Mathis, Barnett S. Meyers

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Background: Among patients with major depression with psychotic features, little is known about the extent to which those with and without somatic delusions differ. Methods: The first 183 participants in the STOP-PD study were divided into two groups based on the presence or absence of somatic delusions and were compared on multiple demographic and clinical characteristics. Results: In the multivariate analysis, those with somatic delusions reported more somatic symptoms, rated their health as worse, and were less likely to have persecutory delusions. Conclusions: Based on the methods we used, we could not detect meaningful differences between subjects with and without somatic delusions. This suggests that the presence of irrational somatic ideation does not define a distinct clinical subgroup among patients with psychotic depression. This finding needs to be replicated.

Original language	English (US)
Pages (from-to)	250-255
Number of pages	6
Journal	Journal of Affective Disorders
Volume	112
Issue number	1-3
DOIs	https://doi.org/10.1016/j.jad.2008.04.008
State	Published - Jan 2009
Externally published	Yes

Keywords

Delusions
Depression
Psychosis
Psychotic depression
Somatization
Subtype

ASJC Scopus subject areas

Clinical Psychology
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.jad.2008.04.008

Cite this

Kamara, T. S., Whyte, E. M., Mulsant, B. H., Peasley-Miklus, C., Rothschild, A. J., Flint, A. J., Heo, M., Papademetriou, E., Mathis, E. R., & Meyers, B. S. (2009). Does major depressive disorder with somatic delusions constitute a distinct subtype of major depressive disorder with psychotic features? Journal of Affective Disorders, 112(1-3), 250-255. https://doi.org/10.1016/j.jad.2008.04.008

Kamara, TS, Whyte, EM, Mulsant, BH, Peasley-Miklus, C, Rothschild, AJ, Flint, AJ, Heo, M, Papademetriou, E, Mathis, ER & Meyers, BS 2009, 'Does major depressive disorder with somatic delusions constitute a distinct subtype of major depressive disorder with psychotic features?', Journal of Affective Disorders, vol. 112, no. 1-3, pp. 250-255. https://doi.org/10.1016/j.jad.2008.04.008

@article{cb3c126c40ee48be8e41073cdbdc2112,

title = "Does major depressive disorder with somatic delusions constitute a distinct subtype of major depressive disorder with psychotic features?",

abstract = "Background: Among patients with major depression with psychotic features, little is known about the extent to which those with and without somatic delusions differ. Methods: The first 183 participants in the STOP-PD study were divided into two groups based on the presence or absence of somatic delusions and were compared on multiple demographic and clinical characteristics. Results: In the multivariate analysis, those with somatic delusions reported more somatic symptoms, rated their health as worse, and were less likely to have persecutory delusions. Conclusions: Based on the methods we used, we could not detect meaningful differences between subjects with and without somatic delusions. This suggests that the presence of irrational somatic ideation does not define a distinct clinical subgroup among patients with psychotic depression. This finding needs to be replicated.",

keywords = "Delusions, Depression, Psychosis, Psychotic depression, Somatization, Subtype",

author = "Kamara, {Taafoi S.} and Whyte, {Ellen M.} and Mulsant, {Benoit H.} and Catherine Peasley-Miklus and Rothschild, {Anthony J.} and Flint, {Alastair J.} and Moonseong Heo and Eros Papademetriou and Mathis, {Erin R.} and Meyers, {Barnett S.}",

note = "Funding Information: Ellen M. Whyte has received research support from the NIMH, Forest Laboratories, Ortho-McNeil, and Pfizer Inc. Funding Information: This research was supported in part by USPHS grants MH30915, MH48512, MH62446, MH62518, MH62565, MH62624, MH069430, MH067710, and M01RR0056 from the National Institute of Health. Eli Lilly and Co. and Pfizer Inc. provided medications for this study. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute Of Mental Health or the National Institutes of Health. Funding Information: Funding for this study or medications were provided by the National Institutes of Health, Eli Lilly and Co., and Pfizer, Inc. as described in the acknowledgments. No sponsor had any further role: in study design; in the collection, analysis and interpretation of data; in the writing of the report; or in the decision to submit the paper for publication. ",

year = "2009",

month = jan,

doi = "10.1016/j.jad.2008.04.008",

language = "English (US)",

volume = "112",

pages = "250--255",

journal = "Journal of Affective Disorders",

issn = "0165-0327",