Differential effects of smoking on lung cancer mortality before and after household stove improvement in Xuanwei, China

K. M. Lee; R. S. Chapman; M. Shen; J. H. Lubin; D. T. Silverman; X. He; H. D. Hosgood; B. E. Chen; P. Rajaraman; N. E. Caporaso; J. F. Fraumeni; A. Blair; Q. Lan

doi:10.1038/sj.bjc.6605791

Differential effects of smoking on lung cancer mortality before and after household stove improvement in Xuanwei, China

K. M. Lee
, R. S. Chapman
, M. Shen
, J. H. Lubin
, D. T. Silverman
, X. He
, H. D. Hosgood
, B. E. Chen
, P. Rajaraman
, N. E. Caporaso
, J. F. Fraumeni
, A. Blair
, Q. Lan

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

Background: In Xuanwei County, Yunnan Province, China, lung cancer mortality rates in both males and females are among the highest in China. Methods: We evaluated differential effects of smoking on lung cancer mortality before and after household stove improvement with chimney to reduce exposure to smoky coal emissions in the unique cohort in Xuanwei, China. Effects of independent variables on lung cancer mortality were measured as hazard ratios and 95% confidence intervals using a multivariable Cox regression model that included separate time-dependent variables for smoking duration (years) before and after stove improvement.Results and conclusion:We found that the effect of smoking on lung cancer risk becomes considerably stronger after chimney installation and consequent reduction of indoor coal smoke exposure.

Original language	English (US)
Pages (from-to)	727-729
Number of pages	3
Journal	British Journal of Cancer
Volume	103
Issue number	5
DOIs	https://doi.org/10.1038/sj.bjc.6605791
State	Published - Aug 2010
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Xuanwei cohort
lung cancer
mortality
smoking
smoky coal
time-dependent variable

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1038/sj.bjc.6605791

Cite this

Lee, K. M., Chapman, R. S., Shen, M., Lubin, J. H., Silverman, D. T., He, X., Hosgood, H. D., Chen, B. E., Rajaraman, P., Caporaso, N. E., Fraumeni, J. F., Blair, A., & Lan, Q. (2010). Differential effects of smoking on lung cancer mortality before and after household stove improvement in Xuanwei, China. British Journal of Cancer, 103(5), 727-729. https://doi.org/10.1038/sj.bjc.6605791

Lee, KM, Chapman, RS, Shen, M, Lubin, JH, Silverman, DT, He, X, Hosgood, HD, Chen, BE, Rajaraman, P, Caporaso, NE, Fraumeni, JF, Blair, A & Lan, Q 2010, 'Differential effects of smoking on lung cancer mortality before and after household stove improvement in Xuanwei, China', British Journal of Cancer, vol. 103, no. 5, pp. 727-729. https://doi.org/10.1038/sj.bjc.6605791

@article{40e7c3fa20a44a66a5e46e19094ca904,

title = "Differential effects of smoking on lung cancer mortality before and after household stove improvement in Xuanwei, China",

abstract = "Background: In Xuanwei County, Yunnan Province, China, lung cancer mortality rates in both males and females are among the highest in China. Methods: We evaluated differential effects of smoking on lung cancer mortality before and after household stove improvement with chimney to reduce exposure to smoky coal emissions in the unique cohort in Xuanwei, China. Effects of independent variables on lung cancer mortality were measured as hazard ratios and 95\% confidence intervals using a multivariable Cox regression model that included separate time-dependent variables for smoking duration (years) before and after stove improvement.Results and conclusion:We found that the effect of smoking on lung cancer risk becomes considerably stronger after chimney installation and consequent reduction of indoor coal smoke exposure.",

keywords = "Xuanwei cohort, lung cancer, mortality, smoking, smoky coal, time-dependent variable",

author = "Lee, \{K. M.\} and Chapman, \{R. S.\} and M. Shen and Lubin, \{J. H.\} and Silverman, \{D. T.\} and X. He and Hosgood, \{H. D.\} and Chen, \{B. E.\} and P. Rajaraman and Caporaso, \{N. E.\} and Fraumeni, \{J. F.\} and A. Blair and Q. Lan",

note = "Funding Information: This study were supported by the Chinese Academy of Preventive Medicine, Beijing, China; Yunnan Province Antiepidemic Station, Kunming, China; US Environmental Protection Agency (contract No 5D2290NFFX); and Intramural Research Programme of the NIH, Division of Cancer Epidemiology and Genetics, National Cancer Institute.",

year = "2010",

month = aug,

doi = "10.1038/sj.bjc.6605791",

language = "English (US)",

volume = "103",

pages = "727--729",

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AU - Lee, K. M.

AU - Chapman, R. S.

AU - Shen, M.

AU - Lubin, J. H.

AU - Silverman, D. T.

AU - He, X.

AU - Hosgood, H. D.

AU - Chen, B. E.

AU - Rajaraman, P.

AU - Caporaso, N. E.

AU - Fraumeni, J. F.

AU - Blair, A.

AU - Lan, Q.

N1 - Funding Information: This study were supported by the Chinese Academy of Preventive Medicine, Beijing, China; Yunnan Province Antiepidemic Station, Kunming, China; US Environmental Protection Agency (contract No 5D2290NFFX); and Intramural Research Programme of the NIH, Division of Cancer Epidemiology and Genetics, National Cancer Institute.

PY - 2010/8

Y1 - 2010/8

N2 - Background: In Xuanwei County, Yunnan Province, China, lung cancer mortality rates in both males and females are among the highest in China. Methods: We evaluated differential effects of smoking on lung cancer mortality before and after household stove improvement with chimney to reduce exposure to smoky coal emissions in the unique cohort in Xuanwei, China. Effects of independent variables on lung cancer mortality were measured as hazard ratios and 95% confidence intervals using a multivariable Cox regression model that included separate time-dependent variables for smoking duration (years) before and after stove improvement.Results and conclusion:We found that the effect of smoking on lung cancer risk becomes considerably stronger after chimney installation and consequent reduction of indoor coal smoke exposure.

AB - Background: In Xuanwei County, Yunnan Province, China, lung cancer mortality rates in both males and females are among the highest in China. Methods: We evaluated differential effects of smoking on lung cancer mortality before and after household stove improvement with chimney to reduce exposure to smoky coal emissions in the unique cohort in Xuanwei, China. Effects of independent variables on lung cancer mortality were measured as hazard ratios and 95% confidence intervals using a multivariable Cox regression model that included separate time-dependent variables for smoking duration (years) before and after stove improvement.Results and conclusion:We found that the effect of smoking on lung cancer risk becomes considerably stronger after chimney installation and consequent reduction of indoor coal smoke exposure.

KW - Xuanwei cohort

KW - lung cancer

KW - mortality

KW - smoking

KW - smoky coal

KW - time-dependent variable

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EP - 729

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JF - British Journal of Cancer

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Differential effects of smoking on lung cancer mortality before and after household stove improvement in Xuanwei, China

Abstract

UN SDGs

Keywords

ASJC Scopus subject areas

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