Diagnosis and Management of Post-PCI Left Circumflex Coronary Artery Pseudoaneurysm

Background: Coronary artery pseudoaneurysms (PSAs) are a rare but potentially life-threatening complication after percutaneous coronary intervention (PCI), typically manifesting between 1 week and 4 years after the procedure. Prompt diagnosis is crucial, particularly in high-risk PSAs, which incur potential for rupture. Case summary: The authors report the case of a 77-year-old man in whom a large PSA developed in the left circumflex artery within 30 days of PCI, which was complicated by coronary perforation. During the original procedure, the perforation was sealed by a covered stent; however, anticoagulation was resumed because of atrial fibrillation 2 weeks later. The patient subsequently presented again with chest discomfort, and computed tomographic angiography showed a large PSA at the edge of the stent. Percutaneous closure using a second covered stent achieved complete PSA isolation. Discussion: This case aims to highlight the importance of precise stent placement, vessel wall apposition, and vigilant follow-up, particularly in patients taking intensive antithrombotic therapy.