Death begets failure in the heart

Roger S.Y. Foo, Kartik Mani, Richard N. Kitsis

Research output: Contribution to journalReview articlepeer-review

269 Scopus citations


Recently, low - but abnormal - rates of cardiomyocyte apoptosis have been observed in failing human hearts. Genetic and pharmacological studies suggest that this cell death is causally linked to heart failure in rodent models. Herein, we review these data and discuss potential therapeutic implications.

Original languageEnglish (US)
Pages (from-to)565-571
Number of pages7
JournalJournal of Clinical Investigation
Issue number3
StatePublished - Mar 2005

ASJC Scopus subject areas

  • General Medicine


Dive into the research topics of 'Death begets failure in the heart'. Together they form a unique fingerprint.

Cite this