TY - JOUR
T1 - DAS28 score vs. Ultrasound examination for assessment of rheumatoid arthritis disease activity
T2 - Comparison and discussion of pros and cons
AU - Barczyńska, Tacjana Anna
AU - Dura, Marta
AU - Blumfield, Einat
AU - Węgierska, Małgorzata
AU - Zuchowski, Pawel
AU - Wilińska-Jankowska, Arnika
AU - Jeka, Sławomir
PY - 2015
Y1 - 2015
N2 - Rheumatoid arthritis (RA) is a chronic systemic connective tissue disease which is characterized by symetrical multiple joints involvement and extra-articular symptoms. Current EULAR diagnostic criteria for RA include disease activity parameters, such as erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), which are used to calculate disease activity scores, including DAS and DAS28. Recently attempts have been made to assess disease activity using imaging diagnostic modalities, such as magnetic resonance imaging (MRI) and ultrasonography (US). Due to significant progress in therapy effectiveness and early RA diagnosis possibility, imaging modalities become increasingly meaningful and many clinical trials confirm their usefulness. However, there are no consistent criteria for objective assessment of therapy effectiveness based on US. Moreover, it is not US availability that limits its common use, but rather significant variability between operators. This is why US remains only an additional tool to assess therapy efficacy with regard to DAS/DAS28 index.
AB - Rheumatoid arthritis (RA) is a chronic systemic connective tissue disease which is characterized by symetrical multiple joints involvement and extra-articular symptoms. Current EULAR diagnostic criteria for RA include disease activity parameters, such as erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), which are used to calculate disease activity scores, including DAS and DAS28. Recently attempts have been made to assess disease activity using imaging diagnostic modalities, such as magnetic resonance imaging (MRI) and ultrasonography (US). Due to significant progress in therapy effectiveness and early RA diagnosis possibility, imaging modalities become increasingly meaningful and many clinical trials confirm their usefulness. However, there are no consistent criteria for objective assessment of therapy effectiveness based on US. Moreover, it is not US availability that limits its common use, but rather significant variability between operators. This is why US remains only an additional tool to assess therapy efficacy with regard to DAS/DAS28 index.
KW - DAS28
KW - Rheumatoid arthritis
KW - Ultrasonography
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U2 - 10.5114/reum.2015.53999
DO - 10.5114/reum.2015.53999
M3 - Review article
AN - SCOPUS:84942315600
SN - 0034-6233
VL - 53
SP - 213
EP - 218
JO - Reumatologia
JF - Reumatologia
IS - 4
ER -