Abstract
An IgG1 monoclonal antibody generated from a mouse infected with Cryptococcus neoformans modified the course of intravenous cryptococcal infection in A/J mice by prolonging survival and reducing lung fungal burden, brain mass, and serum polysaccharide levels. The results demonstrate that C. neoformans infection can elicit useful antibodies.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 888-892 |
| Number of pages | 5 |
| Journal | Canadian Journal of Microbiology |
| Volume | 40 |
| Issue number | 10 |
| DOIs | |
| State | Published - 1994 |
Keywords
- Antibody immunity
- Cryptococcus neoformans
- Monoclonal antibody
ASJC Scopus subject areas
- Microbiology
- Immunology
- Applied Microbiology and Biotechnology
- Molecular Biology
- Genetics
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