@article{a4bf473827eb4849be5c0add274c6641,
title = "COVID-19 in Children With Kidney Disease: A Report of 2 Cases",
abstract = "The presentation of novel coronavirus disease 2019 (COVID-19) in children with kidney disease is largely unknown. We report on 2 children with kidney disease not receiving long-term immunosuppression who were hospitalized due to COVID-19. The first case is an infant with end-stage kidney disease secondary to bilateral cystic dysplastic kidneys and posterior urethral valves receiving peritoneal dialysis, with a history of prematurity previously requiring mechanical ventilation in the neonatal intensive care unit, who presented with fever, hypertension, and emesis. He had no respiratory symptoms and recovered with supportive care. His hypertension was managed well with amlodipine. The second case is a child with steroid-sensitive nephrotic syndrome who presented with a relapse of nephrotic syndrome with concurrent peritonitis and sepsis caused by Streptococcus agalactiae. He was treated with antibiotics and prophylactic anticoagulation therspy. Steroid therapy was initiated after 48 hours of antibiotic therapy. Neither child required mechanical ventilation or developed COVID-19–related multisystem inflammatory syndrome.",
keywords = "COVID19, coronavirus, end-stage kidney disease, nephrotic syndrome, pediatric",
author = "Abby Basalely and Kaye Brathwaite and Duong, {Minh Dien} and Diane Liu and Alexandra Mazo and Yuping Xie and {Del Rio}, Marcela and Beatrice Goilav and Nicole Hayde and Kaskel, {Frederick J.} and Anna Zolotnitskaya and Reidy, {Kimberly J.}",
note = "Funding Information: Abby Basalely, MD, Kaye Brathwaite, MD, Minh Dien Duong, MD, MS, Diane Liu, MD, Alexandra Mazo, MD, PhD, Yuping Xie, MD, MS, Marcela Del Rio, MD, Beatrice Goilav, MD, Nicole Hayde, MD, MS, Frederick J. Kaskel, MD, PhD, Anna Zolotnitskaya, MD, and Kimberly J. Reidy, MD. Drs Basalely, Liu, and Brathwaite are supported by National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases T32DK007110. The authors declare that they have no relevant financial interests. We acknowledge all the members of the Children's Hospital at Montefiore and the Pediatric Nephrology Division who contributed to the care of the patients and manuscript preparation. The authors declare that they have obtained consent from the families of the patients discussed in the report. Received June 17, 2020. Evaluated by 1 external peer reviewer, with direct editorial input from the Editor-in-Chief. Accepted in revised form September 1, 2020. Funding Information: Drs Basalely, Liu, and Brathwaite are supported by National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases T32DK007110 . Publisher Copyright: {\textcopyright} 2020 The Authors",
year = "2021",
month = jan,
day = "1",
doi = "10.1016/j.xkme.2020.09.007",
language = "English (US)",
volume = "3",
pages = "120--123",
journal = "Kidney Medicine",
issn = "2590-0595",
publisher = "Elsevier Inc.",
number = "1",
}