Abstract
Obesity is a chronic disease that increases susceptibility to various diseases, particularly cardiovascular dysfunction, type 2 diabetes, and some types of cancer. In this review, we highlighted recent evidence in mouse models that support a potential benefit of increasing adipose lipid utilization through stimulating lipolysis in adipose tissue and fatty acid oxidation. Brown adipocyte development within white adipose tissue of humans suggests that mouse models may be applicable to human obesity. Consequently, new therapies should target adipose tissue to specifically reduce fat mass through controlled triglyceride utilization.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 588-593 |
| Number of pages | 6 |
| Journal | Current Opinion in Pharmacology |
| Volume | 10 |
| Issue number | 5 |
| DOIs | |
| State | Published - Oct 2010 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
ASJC Scopus subject areas
- Pharmacology
- Drug Discovery
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