TY - JOUR
T1 - Continuous glucose monitoring in the intensive care unit during the COVID-19 pandemic
AU - Agarwal, Shivani
AU - Mathew, Justin
AU - Davis, Georgia M.
AU - Shephardson, Alethea
AU - Levine, Ann
AU - Louard, Rita
AU - Urrutia, Agustina
AU - Perez-Guzman, Citlalli
AU - Umpierrez, Guillermo E.
AU - Peng, Limin
AU - Pasquel, Francisco J.
N1 - Publisher Copyright:
© 2020 by the American Diabetes Association.
PY - 2021
Y1 - 2021
N2 - OBJECTIVE Real-time continuous glucose monitoring (rtCGM) in critically ill hospitalized patients holds promise; however, real-world data are needed. RESEARCH DESIGN AND METHODS We placed Dexcom G6 CGM on intensive care unit (ICU) patients at Montefiore Medical Center with confirmed coronavirus disease 2019 (COVID-19) infection and glycemic variability. We analyzed inpatient CGM accuracy using point-of-care (POC) glucose–CGM matched pairs and included patients for analysis regardless of clinical status. RESULTS We included 11 patients with CGM: 8 on continuous insulin infusion (CII), 8 on vasopressors, 8 intubated, 4 on high-dose glucocorticoids, 6 on renal replacement therapy, and 2 with anasarca. Accuracy was 12.58% for mean and 6.3% for median absolute relative difference. CGM reduced POC testing by ∼60% for patients on CII. CONCLUSIONS In this real-world preliminary analysis of rtCGM during critical illness, we demonstrate early feasibility, considerable accuracy, and meaningful reduction in the frequency of POC glucose testing.
AB - OBJECTIVE Real-time continuous glucose monitoring (rtCGM) in critically ill hospitalized patients holds promise; however, real-world data are needed. RESEARCH DESIGN AND METHODS We placed Dexcom G6 CGM on intensive care unit (ICU) patients at Montefiore Medical Center with confirmed coronavirus disease 2019 (COVID-19) infection and glycemic variability. We analyzed inpatient CGM accuracy using point-of-care (POC) glucose–CGM matched pairs and included patients for analysis regardless of clinical status. RESULTS We included 11 patients with CGM: 8 on continuous insulin infusion (CII), 8 on vasopressors, 8 intubated, 4 on high-dose glucocorticoids, 6 on renal replacement therapy, and 2 with anasarca. Accuracy was 12.58% for mean and 6.3% for median absolute relative difference. CGM reduced POC testing by ∼60% for patients on CII. CONCLUSIONS In this real-world preliminary analysis of rtCGM during critical illness, we demonstrate early feasibility, considerable accuracy, and meaningful reduction in the frequency of POC glucose testing.
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U2 - 10.2337/dc20-2219
DO - 10.2337/dc20-2219
M3 - Article
C2 - 33361145
AN - SCOPUS:85101034742
SN - 0149-5992
VL - 44
SP - 847
EP - 849
JO - Diabetes care
JF - Diabetes care
IS - 3
ER -