Considerations for management of interstitial ectopic pregnancies: Two case reports

Natalia M. Grindler, June Ng, Kristina Tocce, Ruben Alvero

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


Background: Conventional treatment of interstitial pregnancies includes systemic methotrexate, direct methotrexate injection, wedge resection, or hysterectomy. We present two cases of interstitial pregnancies that were successfully managed by different minimally invasive surgical techniques. We also report the novel use of hysteroscopic urologic stone retrieval forceps in the transvaginal removal of persistent products of conception after systemic methotrexate for an interstitial pregnancy. Case presentation: Case 1 was a 28-year-old gravida 1 white woman at 8 weeks gestation; she was diagnosed with a left interstitial pregnancy. After laparoscopic confirmation of the interstitial pregnancy, successful ultrasound-guided suction dilation and curettage was performed. Case 2 was a 33-year-old gravida 3 para 1021 (one term pregnancy, no preterm pregnancies, one ectopic pregnancy and one spontaneous miscarriage, and one living child) Hispanic woman with persistent products of conception after systemic methotrexate for a left interstitial pregnancy. She underwent hysteroscopic-guided removal of the persistent products of conception, which was possible due to novel use of urologic stone retrieval forceps. Conclusions: Successful minimally invasive treatment of interstitial pregnancies may be possible in certain cases. Collaboration between different specialties continues to be important for improving minimally invasive options.

Original languageEnglish (US)
Article number106
JournalJournal of Medical Case Reports
Issue number1
StatePublished - Apr 27 2016
Externally publishedYes


  • Cornual pregnancy
  • Ectopic pregnancy
  • Interstitial pregnancy
  • Minimally invasive surgery
  • Persistent products of conception

ASJC Scopus subject areas

  • General Medicine


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