Complete sequence of a blakpc-2-harboring incfiik1 plasmid from a klebsiella pneumoniae sequence type 258 strain

Liang Chen; Kalyan D. Chavda; Roberto G. Melano; Michael R. Jacobs; Michael H. Levi; Robert A. Bonomo; Barry N. Kreiswirth

doi:10.1128/AAC.02332-12

Complete sequence of a blakpc-2-harboring incfiik1 plasmid from a klebsiella pneumoniae sequence type 258 strain

Liang Chen
, Kalyan D. Chavda
, Roberto G. Melano
, Michael R. Jacobs
, Michael H. Levi
, Robert A. Bonomo
, Barry N. Kreiswirth

Pathology

Research output: Contribution to journal › Article › peer-review

62 Scopus citations

Abstract

We report the nucleotide sequence of a novel bla_KPC-2-harboring IncFII_K1 plasmid, pBK32179, isolated from a carbapenem-resistant Klebsiella pneumoniae ST258 strain from a New York City patient. pBK32179 is 165 kb long, consists of a large backbone of pKPN3-like plasmid, and carries an 18.5-kb bla_KPC-2-containing element that is highly similar to plasmid pKpQIL. pBK32179- like plasmids were identified in 8.3% of strains in a collection of 96 K. pneumoniae isolates from hospitals in the New York City area.

Original language	English (US)
Pages (from-to)	1542-1545
Number of pages	4
Journal	Antimicrobial agents and chemotherapy
Volume	57
Issue number	3
DOIs	https://doi.org/10.1128/AAC.02332-12
State	Published - Mar 2013

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

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10.1128/AAC.02332-12

Cite this

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title = "Complete sequence of a blakpc-2-harboring incfiik1 plasmid from a klebsiella pneumoniae sequence type 258 strain",

abstract = "We report the nucleotide sequence of a novel blaKPC-2-harboring IncFIIK1 plasmid, pBK32179, isolated from a carbapenem-resistant Klebsiella pneumoniae ST258 strain from a New York City patient. pBK32179 is 165 kb long, consists of a large backbone of pKPN3-like plasmid, and carries an 18.5-kb blaKPC-2-containing element that is highly similar to plasmid pKpQIL. pBK32179- like plasmids were identified in 8.3\% of strains in a collection of 96 K. pneumoniae isolates from hospitals in the New York City area.",

author = "Liang Chen and Chavda, \{Kalyan D.\} and Melano, \{Roberto G.\} and Jacobs, \{Michael R.\} and Levi, \{Michael H.\} and Bonomo, \{Robert A.\} and Kreiswirth, \{Barry N.\}",

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language = "English (US)",

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AU - Chen, Liang

AU - Chavda, Kalyan D.

AU - Melano, Roberto G.

AU - Jacobs, Michael R.

AU - Levi, Michael H.

AU - Bonomo, Robert A.

AU - Kreiswirth, Barry N.

PY - 2013/3

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AB - We report the nucleotide sequence of a novel blaKPC-2-harboring IncFIIK1 plasmid, pBK32179, isolated from a carbapenem-resistant Klebsiella pneumoniae ST258 strain from a New York City patient. pBK32179 is 165 kb long, consists of a large backbone of pKPN3-like plasmid, and carries an 18.5-kb blaKPC-2-containing element that is highly similar to plasmid pKpQIL. pBK32179- like plasmids were identified in 8.3% of strains in a collection of 96 K. pneumoniae isolates from hospitals in the New York City area.

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IS - 3

ER -

Complete sequence of a blakpc-2-harboring incfiik1 plasmid from a klebsiella pneumoniae sequence type 258 strain

Abstract

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