Complement C3 and Autophagy Keep the β Cell Alive

Miriam Toledo, Rajat Singh

Research output: Contribution to journalShort surveypeer-review

5 Scopus citations


Autophagy prevents pancreatic β cell death during obesity, although the mechanism of autophagy activation in the β cell has remained elusive. In this issue of Cell Metabolism, King et al. (2018) show that intracellular complement component C3 interacts with autophagy protein ATG16L1 and protects against β cell death by stimulating autophagy.

Original languageEnglish (US)
Pages (from-to)4-6
Number of pages3
JournalCell metabolism
Issue number1
StatePublished - Jan 8 2019

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology


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