Complement C3 and Autophagy Keep the β Cell Alive

Miriam Toledo; Rajat Singh

doi:10.1016/j.cmet.2018.12.010

Complement C3 and Autophagy Keep the β Cell Alive

Miriam Toledo, Rajat Singh

Medicine

Research output: Contribution to journal › Short survey › peer-review

5 Scopus citations

Abstract

Autophagy prevents pancreatic β cell death during obesity, although the mechanism of autophagy activation in the β cell has remained elusive. In this issue of Cell Metabolism, King et al. (2018) show that intracellular complement component C3 interacts with autophagy protein ATG16L1 and protects against β cell death by stimulating autophagy.

Original language	English (US)
Pages (from-to)	4-6
Number of pages	3
Journal	Cell metabolism
Volume	29
Issue number	1
DOIs	https://doi.org/10.1016/j.cmet.2018.12.010
State	Published - Jan 8 2019

ASJC Scopus subject areas

Physiology
Molecular Biology
Cell Biology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.cmet.2018.12.010

Cite this

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title = "Complement C3 and Autophagy Keep the β Cell Alive",

abstract = "Autophagy prevents pancreatic β cell death during obesity, although the mechanism of autophagy activation in the β cell has remained elusive. In this issue of Cell Metabolism, King et al. (2018) show that intracellular complement component C3 interacts with autophagy protein ATG16L1 and protects against β cell death by stimulating autophagy.",

author = "Miriam Toledo and Rajat Singh",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",

year = "2019",

month = jan,

day = "8",

doi = "10.1016/j.cmet.2018.12.010",

language = "English (US)",

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pages = "4--6",

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TY - JOUR

T1 - Complement C3 and Autophagy Keep the β Cell Alive

AU - Toledo, Miriam

AU - Singh, Rajat

PY - 2019/1/8

Y1 - 2019/1/8

N2 - Autophagy prevents pancreatic β cell death during obesity, although the mechanism of autophagy activation in the β cell has remained elusive. In this issue of Cell Metabolism, King et al. (2018) show that intracellular complement component C3 interacts with autophagy protein ATG16L1 and protects against β cell death by stimulating autophagy.

AB - Autophagy prevents pancreatic β cell death during obesity, although the mechanism of autophagy activation in the β cell has remained elusive. In this issue of Cell Metabolism, King et al. (2018) show that intracellular complement component C3 interacts with autophagy protein ATG16L1 and protects against β cell death by stimulating autophagy.

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U2 - 10.1016/j.cmet.2018.12.010

DO - 10.1016/j.cmet.2018.12.010

M3 - Short survey

C2 - 30625308

AN - SCOPUS:85059241422

SN - 1550-4131

VL - 29

SP - 4

EP - 6

JO - Cell metabolism

JF - Cell metabolism

IS - 1

ER -

Complement C3 and Autophagy Keep the β Cell Alive

Abstract

ASJC Scopus subject areas

UN SDGs

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