Collagen cross-linking for pediatric refractive correction

Research output: Contribution to journalReview articlepeer-review


Corneal collagen-crosslinking (CXL) has been widely investigated in the adult population. There is still little available in the literature, however, on the effects of CXL in children. A review of the literature on CXL in the pediatric population is presented here, with a particular emphasis on the refractive effects. Although several studies demonstrate promising results, most studies have small sample sizes with relatively short follow-up periods. Further investigation on the effects of CXL in the pediatric population is required to better understand long-term effects.

Original languageEnglish (US)
Article number4632
JournalAnnals of Eye Science
Issue number12
StatePublished - Dec 1 2018


  • Corneal collagen-crosslinking (CXL)
  • Keratoconus
  • Pediatric refractive correction

ASJC Scopus subject areas

  • Ophthalmology


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