Abstract
Background: To the best of our knowledge, the association of physical impairment and cognitive decline has never been investigated in frail patients with acute myocardial infarction. Aim: The aim of our study is to assess the correlation between physical and cognitive dysfunction in frail patients with ST-elevation myocardial infarction (STEMI). Methods: We examined consecutive frail patients with first STEMI treated with primary percutaneous coronary intervention (PPCI). All patients were evaluated via Mini Mental State Examination (MMSE) and 5-m gait speed test after PPCI. Results: A total of 871 frail patients with suspected STEMI were admitted and 301 patients successfully completed the study. We found that the gait speed significantly correlated with the MMSE score (r: 0.771; p: < 0.001). The independent effects on MMSE score were confirmed in a linear multivariate analysis. Conclusions: Taken together, our findings indicate that an assessment of both cognitive and physical conditions should be included in the comprehensive geriatric evaluation of hospitalized older STEMI patients.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 49-53 |
| Number of pages | 5 |
| Journal | Aging Clinical and Experimental Research |
| Volume | 34 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2022 |
Keywords
- Cognitive decline
- Frailty
- Gait speed test
- STEMI
ASJC Scopus subject areas
- Aging
- Geriatrics and Gerontology
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