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Chronic cavitary pulmonary histoplasmosis treated with isavuconazole after a hypersensitivity reaction to itraconazole

Research output: Contribution to journal › Article › peer-review

Abstract

Chronic cavitary pulmonary histoplasmosis requires prolonged treatment with itraconazole. However, hypersensitivity reactions to itraconazole, though rare, pose a challenge due to limited data on the efficacy and cross-reactivity of the newer azoles. We present a case of chronic cavitary pulmonary histoplasmosis successfully treated with isavuconazole following an itraconazole-induced hypersensitivity reaction, highlighting its potential as an alternative therapy in such cases.

Original languageEnglish (US)
Article number100711
JournalMedical Mycology Case Reports
Volume49
DOIs
StatePublished - Sep 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Cross-reaction
  • Histoplasmosis
  • Hypersensitivity
  • Isavuconazole
  • Itraconazole

ASJC Scopus subject areas

  • Microbiology
  • Infectious Diseases

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