TY - JOUR
T1 - Chemotherapy-induced hand-foot syndrome and nail changes
T2 - A review of clinical presentation, etiology, pathogenesis, and management
AU - Miller, Kristen K.
AU - Gorcey, Loren
AU - McLellan, Beth N.
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2014
Y1 - 2014
N2 - Chemotherapy-induced hand-foot syndrome and nail changes are common complications of many classic chemotherapeutic agents and the newer molecular targeted therapies. They significantly impact patient quality of life, and frequently necessitate chemotherapy dose intensity modification or reduction. We aim to describe the epidemiology, pathogenesis, clinical presentation, and current evidence-based treatment options for these entities. ( J Am Acad Dermatol 2014;71:787-94.).
AB - Chemotherapy-induced hand-foot syndrome and nail changes are common complications of many classic chemotherapeutic agents and the newer molecular targeted therapies. They significantly impact patient quality of life, and frequently necessitate chemotherapy dose intensity modification or reduction. We aim to describe the epidemiology, pathogenesis, clinical presentation, and current evidence-based treatment options for these entities. ( J Am Acad Dermatol 2014;71:787-94.).
KW - Chemotherapy complications
KW - Chemotherapy nail complications
KW - Hand-foot skin reaction
KW - Hand-foot syndrome
KW - Molecular targeted therapy complications
KW - Palmoplantar erythrodysesthesia
UR - http://www.scopus.com/inward/record.url?scp=84910113008&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84910113008&partnerID=8YFLogxK
U2 - 10.1016/j.jaad.2014.03.019
DO - 10.1016/j.jaad.2014.03.019
M3 - Review article
C2 - 24795111
AN - SCOPUS:84910113008
SN - 0190-9622
VL - 71
SP - 787
EP - 794
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
IS - 4
ER -