Central venous catheter related sepsis: a clinical review

Chaim Putterman

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Central venous catheterization is one of the most common invasive vascular procedures performed in hospitals today. Though catheter related sepsis occurs only in a small percentage of catheterized patients, this complication has a tremendous impact due to the ubiquitous use of central venous catheters and consequent morbidity and even mortality. Recent studies have considerably advanced our knowledge regarding the pathogenesis, diagnosis, and prevention of catheter sepsis. In this paper, current concepts regarding cather-related sepsis are reviewed, regarding the incidence, pathophysiology, diagnosis, prevention, and therapy of this complication. Particular emphasis is placed upon recent research and clinical advances in this field, which have clarified important question and suggested promising approaches to the prevention and treatment of catheter bacteremia. The excessive morbidity and mortality due to catheter-related sepsis can be markedly decreased, by attention to simple infection control methods, and by future implementation of new experimental techniques.

Original languageEnglish (US)
Pages (from-to)1-16
Number of pages16
Issue number1
StatePublished - Aug 1990
Externally publishedYes


  • Catherter related sepsis
  • Catheterization
  • Catheterization complications
  • Central venous catheters
  • Nosocomial infections
  • Sepsis

ASJC Scopus subject areas

  • Emergency Medicine
  • Emergency
  • Cardiology and Cardiovascular Medicine


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